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治疗性镜片的基弧及其对Epi-LASIK术后视力和疼痛的影响:一项前瞻性随机临床试验。

Base curves of therapeutic lenses and their effects on post Epi-LASIK vision and pain: a prospective randomized clinical trial.

作者信息

Kim Jung-Sub, Na Kyung-Sun, Joo Choun-Ki

机构信息

Department of Ophthalmology and Visual Science, Kangnam St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

出版信息

Jpn J Ophthalmol. 2009 Jul;53(4):368-73. doi: 10.1007/s10384-009-0672-9. Epub 2009 Sep 8.

DOI:10.1007/s10384-009-0672-9
PMID:19763753
Abstract

PURPOSE

To compare the efficacy of bandage contact lenses with two different base curves in promoting epithelial healing after epithelial laser in situ keratomileusis (epi-LASIK).

METHODS

A prospective, observer-masked study was conducted in 27 patients. Each patient randomly received one bandage contact lens with an 8.4-mm base curve in one eye and one with an 8.8-mm base curve in the fellow eye. Corneal epithelial status, pain score, spherical equivalent, and uncorrected visual acuity (UCVA) were examined during the first postoperative month.

RESULTS

Corneal epithelial status, postoperative pain, and spherical equivalent were similar for both lenses during the first postoperative month. The eyes with lenses with an 8.8-mm base curve had better UCVA on postoperative day (POD) 4, but there was no significant difference in UCVA after POD 7. In the patients with preoperative low to moderate myopia and low keratometric values (<43.0 D), there was no significant difference in the postoperative UCVA between the lenses. On the other hand, in patients with preoperative high myopia and high keratometric values (> or =43.0 D), UCVA was better in eyes with lenses with an 8.8-mm base curve on POD 4.

CONCLUSIONS

These findings suggest that the base curves of bandage contact lenses affect visual rehabilitation after epi-LASIK, particularly in patients with a steep cornea and high myopia.

摘要

目的

比较两种不同基弧的绷带式隐形眼镜在准分子激光上皮下角膜磨镶术(epi-LASIK)后促进上皮愈合的疗效。

方法

对27例患者进行前瞻性、观察者盲法研究。每位患者一只眼随机佩戴基弧为8.4毫米的绷带式隐形眼镜,另一只眼佩戴基弧为8.8毫米的绷带式隐形眼镜。在术后第一个月内检查角膜上皮状态、疼痛评分、等效球镜度和裸眼视力(UCVA)。

结果

术后第一个月,两种镜片的角膜上皮状态、术后疼痛和等效球镜度相似。基弧为8.8毫米的镜片组在术后第4天的UCVA更好,但术后第7天之后UCVA无显著差异。术前为低度至中度近视且角膜曲率值较低(<43.0 D)的患者,两种镜片术后的UCVA无显著差异。另一方面,术前为高度近视且角膜曲率值较高(≥43.0 D)的患者,基弧为8.8毫米的镜片组在术后第4天的UCVA更好。

结论

这些发现表明,绷带式隐形眼镜的基弧会影响epi-LASIK术后的视力恢复,尤其是在角膜陡峭和高度近视患者中。

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Effects of lotrafilcon A and omafilcon A bandage contact lenses on visual outcomes after photorefractive keratectomy.洛替康 A 和奥马菲康 A 绷带式隐形眼镜对屈光性角膜切削术后视觉效果的影响。
J Cataract Refract Surg. 2008 Aug;34(8):1288-94. doi: 10.1016/j.jcrs.2008.04.024.
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Corneal stability after discontinued soft contact lens wear.停用软性隐形眼镜后角膜的稳定性。
Cont Lens Anterior Eye. 2008 Jun;31(3):122-5. doi: 10.1016/j.clae.2008.02.001. Epub 2008 Mar 14.
3
Comparison of silicone and non-silicone hydrogel soft contact lenses used as a bandage after LASEK.
准分子激光上皮下角膜磨镶术(LASEK)后用作绷带的硅水凝胶和非硅水凝胶软性接触镜的比较。
J Refract Surg. 2008 Feb;24(2):199-203. doi: 10.3928/1081597X-20080201-12.
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Effect of base curve radius of therapeutic lenses on epithelial healing after laser-assisted subepithelial keratectomy.治疗性镜片的基弧半径对激光辅助上皮下角膜磨镶术后上皮愈合的影响。
Korean J Ophthalmol. 2007 Jun;21(2):85-9. doi: 10.3341/kjo.2007.21.2.85.
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Assessment of epithelial integrity and cell viability in epithelial flaps prepared with the epi-LASIK procedure.
J Cataract Refract Surg. 2007 Jul;33(7):1195-200. doi: 10.1016/j.jcrs.2007.03.038.
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Epi-LASIK: histological findings of separated epithelial sheets 24 hours after treatment.
J Refract Surg. 2006 Feb;22(2):151-4. doi: 10.3928/1081-597X-20060201-12.
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US trends in refractive surgery: 2004 ISRS/AAO Survey.美国屈光手术趋势:2004年国际屈光手术学会/美国眼科学会调查
J Refract Surg. 2005 Nov-Dec;21(6):742-8. doi: 10.3928/1081-597X-20051101-14.
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Adverse events with silicone hydrogel continuous wear.硅水凝胶持续佩戴的不良事件。
Cont Lens Anterior Eye. 2002 Sep;25(3):137-46. doi: 10.1016/s1367-0484(02)00009-7.
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Therapeutic contact lenses.治疗性隐形眼镜。
Cont Lens Anterior Eye. 1999;22 Suppl 1:S20-5. doi: 10.1016/s1367-0484(99)80039-3.
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Wound healing in the cornea: a review of refractive surgery complications and new prospects for therapy.角膜伤口愈合:屈光手术并发症综述与治疗新前景
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