Gil-Cazorla Raquel, Teus Miguel A, Arranz-Márquez Esther
Vissum Corporación Oftalmológica de Madrid, C/ Santa Hortensia, 58, 28002, Madrid, Spain.
J Refract Surg. 2008 Feb;24(2):199-203. doi: 10.3928/1081597X-20080201-12.
To evaluate two different soft contact lens materials for continuous-wear bandage contact lenses after laser epithelial keratomileusis (LASEK).
A prospective, observer-masked study was conducted of 32 eyes of 16 consecutive patients. Inclusion criteria were candidates for bilateral LASEK, myopia of < or = -6.00 diopters (D), astigmatism < -1.50 D, and bilateral best spectacle-corrected visual acuity of 20/20 or better. Patients were randomly selected for a balafilcon A (PureVision; Bausch & Lomb) bandage contact lens in one eye and a poly-2-hydroxyethylmethacrylate-co-methacrylate glycerol (EquiS 60; mark'ennovy) in the fellow eye. Corneal epithelial status, conjunctival and limbal hyperemia, lens movement, contact lens debris, and the responses to a subjective comfort questionnaire were assessed postoperatively. The parameters were evaluated preoperatively and 1 and 5 days postoperatively. Paired Student t test and chi-square tests were used when appropriate.
Thirty-two eyes of 16 consecutive patients who underwent LASEK to correct low to moderate myopia were analyzed. The mean spherical equivalent refraction was -3.25 D. There was no difference in conjunctival or limbal hyperemia, contact lens debris, or subjective comfort between lenses at any postoperative visit. In contrast, the corneal epithelial status was statistically better in the eyes with a silicone bandage contact lens 5 days after LASEK (P = .01).
The results suggest that the bandage contact lens material used after LASEK affects the corneal epithelial healing process.
评估两种不同的软性接触镜材料用于准分子激光上皮下角膜磨镶术（LASEK）后连续佩戴的绷带式接触镜。
对16例连续患者的32只眼进行前瞻性、观察者盲法研究。纳入标准为双侧LASEK手术候选者，近视度数≤-6.00屈光度（D），散光＜-1.50 D，且双眼最佳矫正视力为20/20或更好。患者被随机选择，一只眼佩戴balafilcon A（PureVision；博士伦）绷带式接触镜，另一只眼佩戴聚甲基丙烯酸2-羟乙酯-甲基丙烯酸甘油酯（EquiS 60；mark'ennovy）。术后评估角膜上皮状态、结膜和角膜缘充血、镜片移动、接触镜碎片以及主观舒适度问卷的回答情况。术前、术后1天和5天评估这些参数。适当情况下使用配对学生t检验和卡方检验。
分析了16例连续接受LASEK矫正低度至中度近视患者的32只眼。平均等效球镜度为-3.25 D。术后任何一次随访时，两种镜片在结膜或角膜缘充血、接触镜碎片或主观舒适度方面均无差异。相比之下，LASEK术后5天，佩戴硅水凝胶绷带式接触镜的眼的角膜上皮状态在统计学上更好（P = 0.01）。
结果表明，LASEK术后使用的绷带式接触镜材料会影响角膜上皮愈合过程。
