Retina Foundation of the Southwest, Dallas and Memorial University, Dallas, TX, USA.
Child Dev. 2009 Sep-Oct;80(5):1376-84. doi: 10.1111/j.1467-8624.2009.01339.x.
This study examines whether feeding infants formula supplemented with long-chain polyunsaturated fatty acids (LCPUFA) improves cognitive function of 9-month-olds. Participants included 229 infants from 3 randomized controlled trials. Children received either formula supplemented with docosahexaenoic acid and arachidonic acid, or a control formula beginning at 1-5 days (12-month feeding study), or following 6 weeks (6-week-weaning study) or 4-6 months of breastfeeding (4-to 6-month weaning study). Infants were assessed with a 2-step problem solving task. In the 12-month feeding and 6-week weaning studies, supplemented children had more intentional solutions (successful task completions) and higher intention scores (goal-directed behaviors) than controls. These results suggest that LCPUFA supplementation improves means-end problem solving.
本研究旨在探究在婴儿配方奶粉中添加长链多不饱和脂肪酸（LCPUFA）是否能改善 9 月龄婴儿的认知功能。研究对象为来自三项随机对照试验的 229 名婴儿。儿童从 1-5 天（12 个月喂养研究）开始接受添加二十二碳六烯酸（DHA）和花生四烯酸（ARA）的配方奶粉或对照配方奶粉，或在 6 周（6 周断奶研究）或 4-6 个月母乳喂养（4-6 个月断奶研究）后接受配方奶粉。婴儿接受了两步式解决问题任务的评估。在 12 个月喂养和 6 周断奶研究中，补充组儿童的有意解决方案（成功完成任务）和更高的意图得分（目标导向行为）均多于对照组。这些结果表明，LCPUFA 补充可改善手段-目的问题解决能力。
