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植物着丝粒概述。

An overview of plant centromeres.

作者信息

Wang Guixiang, Zhang Xueyong, Jin Weiwei

机构信息

National Maize Improvement Center of China, Key Laboratory of Crop Genetic Improvement and Genome of Ministry of Agriculture, Beijing Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing 100094, China.

出版信息

J Genet Genomics. 2009 Sep;36(9):529-37. doi: 10.1016/S1673-8527(08)60144-7.

Abstract

The centromere is a defining region that mediates chromosome attachment to kinetochore microtubules and proper segregation of the sister chromatids. Intriguingly, satellite DNA and centromeric retrotransposon as major DNA constituents of centromere showed baffling diversification and species-specific. However, the key kinetochore proteins are conserved in both plants and animals, particularly the centromere-specific histone H3-like protein (CENH3) in all functional centromeres. Recent studies have highlighted the importance of epigenetic mechanisms in the establishment and maintenance of centromere identity. Here, we review the progress and compendium of research on plant centromere in the light of recent data.

摘要

着丝粒是一个决定性区域,它介导染色体与动粒微管的附着以及姐妹染色单体的正确分离。有趣的是,卫星DNA和着丝粒逆转座子作为着丝粒的主要DNA成分,呈现出令人困惑的多样化和物种特异性。然而,关键的动粒蛋白在植物和动物中都是保守的,尤其是所有功能着丝粒中的着丝粒特异性组蛋白H3样蛋白(CENH3)。最近的研究强调了表观遗传机制在着丝粒身份确立和维持中的重要性。在此,我们根据最新数据综述植物着丝粒的研究进展和概要。

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