Yale-New Haven Hospital, New Haven, Connecticut, USA.
Surv Ophthalmol. 2010 Jan-Feb;55(1):89-100. doi: 10.1016/j.survophthal.2009.06.005.
In antiquity the aqueous humor was seen as essential to moisten and nourish the lens- the actual organ of vision-and therefore any loss was believed to lead to blindness. The recuperation of the eye after some aqueous loss during cataract couching and experimental loss in animals slowly undermined this idea in the 16(th) and 17(th) centuries. In the 18(th) century production of aqueous from the ciliary region and its outflow from the anterior chamber, and thus its circulation, was generally accepted. Early in the 19(th) century the aqueous was thought to be encapsulated, but by the end of the century the general dynamic principles of aqueous flow as we know them today were experimentally and clinically confirmed. The controversy concerning its mode of production and circulation that took place early in the 20(th) century was resolved with the discovery of the aqueous veins and advances in molecular biology.
在古代，人们认为房水对于滋润和滋养晶状体——即真正的视觉器官——至关重要，因此任何房水的流失都被认为会导致失明。在 16 世纪和 17 世纪，白内障囊外摘出术和动物实验中房水的部分流失后眼睛的恢复，缓慢地动摇了这一观点。18 世纪，人们普遍接受房水是从睫状区产生并从前房流出，从而实现循环。19 世纪早期，人们认为房水是被包裹的，但到 19 世纪末，我们今天所知道的房水流动的一般动力学原理已通过实验和临床得到证实。20 世纪早期关于房水产生和循环方式的争议随着房水静脉的发现和分子生物学的进步而得到解决。
