年龄相关性点状白内障的患病率及其相关因素：北京眼病研究。

Prevalence and associations of asteroid hyalosis: the Beijing Eye Study.

机构信息

Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

出版信息

BMC Ophthalmol. 2022 Sep 6;22(1):360. doi: 10.1186/s12886-022-02586-6.

DOI:10.1186/s12886-022-02586-6

PMID:36068511

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9446789/

Abstract

BACKGROUND

To determine the prevalence and associations of asteroid hyalosis (AH) in a Chinese population-based cohort.

METHODS

The retrospective, cross-sectional, population-based Beijing Eye Study 2011 included 3468 individuals with a mean age of 64.6 ± 9.8 years (range: 50-93 years). Participants underwent detailed ophthalmic examinations including fundus photographs for diagnosis of AH. Data on systemic and ocular factors were collected for all participants according to the standardized protocol. Multiple linear regression and multivariate Logistic regression analysis were performed.

RESULTS

Fundus photographs were gradable in 3419 subjects. AH was detected in 63 (0.9%, 95% CI: 0.7%, 1.1%) eyes of 53 (1.6%, 95% CI: 1.1%, 2.0%) subjects. AH was bilateral in 18.9%. Mean age of all subjects with AH was 69.2 ± 9.5 years (median, 71.0 years; range, 51-91 years), mean spherical equivalent was 0.63 ± 1.53D (median, 0.75 D; range, -4.12 to 4.00D). In multivariate analysis, prevalence of AH was associated with elder age (P = 0.014, OR 1.057), thicker lens (P = 0.032, OR 3.887), higher spherical equivalent (P = 0.017, OR 1.396).

CONCLUSIONS

In adult Chinese in Beijing, the prevalence of AH was 0.9% for eyes or 1.6% for subjects. AH was associated with elder age, thicker lens, and higher spherical equivalent. It was not associated with diabetes or other systemic indicators.

摘要

背景

旨在确定中国人群中星状玻璃体混浊（AH）的患病率及其相关因素。

方法

回顾性、横断面、基于人群的北京眼研究 2011 纳入了 3468 名平均年龄为 64.6±9.8 岁（范围：50-93 岁）的个体。参与者接受了详细的眼科检查，包括眼底照片以诊断 AH。根据标准化方案收集了所有参与者的系统和眼部因素数据。进行了多元线性回归和多变量 Logistic 回归分析。

结果

3419 名受试者的眼底照片可分级。在 53 名（1.6%，95%CI：1.1%，2.0%）受试者的 63 只（0.9%，95%CI：0.7%，1.1%）眼中检测到 AH。18.9%的病例为双侧。所有患有 AH 的受试者的平均年龄为 69.2±9.5 岁（中位数，71.0 岁；范围，51-91 岁），平均等效球镜为 0.63±1.53D（中位数，0.75 D；范围，-4.12 至 4.00D）。在多变量分析中，AH 的患病率与年龄较大（P=0.014，OR 1.057）、晶状体较厚（P=0.032，OR 3.887）、等效球镜较高（P=0.017，OR 1.396）相关。