过氧化氢酶-过氧化物酶KatG对于野油菜黄单胞菌野油菜致病变种在寄主植物中的致病性是必需的，它通过提供对低水平过氧化氢的保护作用来实现。
The catalase-peroxidase KatG is required for virulence of Xanthomonas campestris pv. campestris in a host plant by providing protection against low levels of H2O2.
作者信息
Jittawuttipoka Thichakorn, Buranajitpakorn Sarinya, Vattanaviboon Paiboon, Mongkolsuk Skorn
机构信息
Department of Biotechnology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
出版信息
J Bacteriol. 2009 Dec;191(23):7372-7. doi: 10.1128/JB.00788-09. Epub 2009 Sep 25.
Abstract
Xanthomonas campestris pv. campestris katG encodes a catalase-peroxidase that has a role in protecting the bacterium against micromolar concentrations of H(2)O(2). A knockout mutation in katG that causes loss of catalase-peroxidase activity correlates with increased susceptibility to H(2)O(2) and a superoxide generator and is avirulent in a plant model system. katG expression is induced by oxidants in an OxyR-dependent manner.
摘要
野油菜黄单胞菌野油菜致病变种的katG编码一种过氧化氢酶-过氧化物酶，该酶在保护细菌免受微摩尔浓度的H₂O₂影响方面发挥作用。katG中的敲除突变导致过氧化氢酶-过氧化物酶活性丧失，这与对H₂O₂和超氧化物产生剂的敏感性增加相关，并且在植物模型系统中无毒性。katG的表达由氧化剂以OxyR依赖的方式诱导。
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