Department of Oral and Maxillofacial Sciences, Graduate School of Medicine, Gifu University, Gifu, Japan.
Antimicrob Agents Chemother. 2009 Dec;53(12):5308-11. doi: 10.1128/AAC.00630-09. Epub 2009 Sep 28.
Antimicrobial susceptibilities of 23 strains of Desulfovibrio spp. were tested by Etest. Generally, Desulfovibrio spp. were highly susceptible to sulbactam-ampicillin, meropenem, clindamycin, metronidazole, and chloramphenicol: MIC(90)s of 6, 4, 0.19, 0.25, and 8 microg/ml, respectively. In addition, these strains generally showed high MICs to piperacillin and piperacillin-tazobactam. Desulfovibrio fairfieldensis (eight strains) was the species least susceptible to most agents, especially beta-lactams, and was the only species resistant to fluoroquinolones. Desulfovibrio desulfuricans strain Essex 6 isolates were less susceptible to beta-lactams than D. desulfuricans strain MB isolates.
采用 Etest 法对 23 株脱硫弧菌属的抗菌药敏性进行了检测。总体而言，脱硫弧菌属对舒巴坦-氨苄西林、美罗培南、克林霉素、甲硝唑和氯霉素高度敏感：MIC90 分别为 6、4、0.19、0.25 和 8μg/ml。此外，这些菌株通常对哌拉西林和哌拉西林-他唑巴坦表现出较高的 MIC 值。费尔菲尔德脱硫弧菌（8 株）是对大多数药物（尤其是β-内酰胺类药物）敏感性最低的菌种，也是唯一对氟喹诺酮类药物耐药的菌种。脱硫脱硫弧菌 Essex 6 分离株比脱硫脱硫弧菌 MB 分离株对β-内酰胺类药物的敏感性更低。
