从人类中分离的 23 株脱硫弧菌的药敏试验
Susceptibilities of 23 Desulfovibrio isolates from humans.
机构信息
Department of Oral and Maxillofacial Sciences, Graduate School of Medicine, Gifu University, Gifu, Japan.
出版信息
Antimicrob Agents Chemother. 2009 Dec;53(12):5308-11. doi: 10.1128/AAC.00630-09. Epub 2009 Sep 28.
Abstract
Antimicrobial susceptibilities of 23 strains of Desulfovibrio spp. were tested by Etest. Generally, Desulfovibrio spp. were highly susceptible to sulbactam-ampicillin, meropenem, clindamycin, metronidazole, and chloramphenicol: MIC(90)s of 6, 4, 0.19, 0.25, and 8 microg/ml, respectively. In addition, these strains generally showed high MICs to piperacillin and piperacillin-tazobactam. Desulfovibrio fairfieldensis (eight strains) was the species least susceptible to most agents, especially beta-lactams, and was the only species resistant to fluoroquinolones. Desulfovibrio desulfuricans strain Essex 6 isolates were less susceptible to beta-lactams than D. desulfuricans strain MB isolates.
摘要
采用 Etest 法对 23 株脱硫弧菌属的抗菌药敏性进行了检测。总体而言，脱硫弧菌属对舒巴坦-氨苄西林、美罗培南、克林霉素、甲硝唑和氯霉素高度敏感：MIC90 分别为 6、4、0.19、0.25 和 8μg/ml。此外，这些菌株通常对哌拉西林和哌拉西林-他唑巴坦表现出较高的 MIC 值。费尔菲尔德脱硫弧菌（8 株）是对大多数药物（尤其是β-内酰胺类药物）敏感性最低的菌种，也是唯一对氟喹诺酮类药物耐药的菌种。脱硫脱硫弧菌 Essex 6 分离株比脱硫脱硫弧菌 MB 分离株对β-内酰胺类药物的敏感性更低。
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