老年乳腺癌患者的辅助治疗：提供最佳治愈机会。
Adjuvant Treatment of Elderly Breast Cancer Patients: Offer the Best Chances of Cure.
作者信息
Marinopoulos Spyridon, Dimitrakakis Constantine, Kalampalikis Andreas, Zagouri Flora, Andrikopoulou Angeliki, Rodolakis Alexandros
机构信息
Breast Unit, 1st Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece.
Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece.
出版信息
Breast Care (Basel). 2022 Feb;17(1):71-80. doi: 10.1159/000513708. Epub 2021 Mar 4.
BACKGROUND
Breast cancer remains the most common cancer in women and a leading cause of death. Elderly people have a higher incidence of breast cancer since it increases with age. Furthermore, the extended life expectancy and advances in imaging techniques have led to an increased number of cases. Guidelines concerning the management of this specific age group are rare, mainly due to underrepresentation of seniors in clinical trials. Moreover, increased frailty, comorbidities, and a poor performance status make it complex to determine the best therapeutic approach.
SUMMARY
In this review, we attempt to summarize the current literature and aim to provide specific approaches and recommendations for prompt diagnosis, treatment, and management of breast cancer in the elderly.
KEY MESSAGES
The establishment of applicable protocols is imperative and efforts are being made in this direction. A careful geriatric assessment and adequate consultation should be the standard of care and patient's preferences should always be considered.
背景
乳腺癌仍然是女性中最常见的癌症，也是主要的死亡原因。老年人患乳腺癌的发病率更高，因为其发病率会随着年龄增长而上升。此外，预期寿命的延长和成像技术的进步导致病例数量增加。关于这一特定年龄组管理的指南很少，主要是因为老年人在临床试验中的代表性不足。此外，身体虚弱、合并症增加以及功能状态不佳使得确定最佳治疗方法变得复杂。
总结
在本综述中，我们试图总结当前的文献，并旨在为老年乳腺癌的快速诊断、治疗和管理提供具体方法和建议。
关键信息
制定适用的方案势在必行，目前正在朝着这个方向努力。仔细的老年医学评估和充分的会诊应成为护理标准，并且应始终考虑患者的偏好。
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