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五种市售抗破伤风类毒素免疫球蛋白G酶联免疫吸附测定法的比较。

Comparison of five commercial anti-tetanus toxoid immunoglobulin G enzyme-linked immunosorbent assays.

作者信息

Perry A L, Hayes A J, Cox H A, Alcock F, Parker A R

机构信息

The Binding Site Group Limited, P.O. Box 11712, Birmingham B14 4ZB, United Kingdom.

出版信息

Clin Vaccine Immunol. 2009 Dec;16(12):1837-9. doi: 10.1128/CVI.00294-09. Epub 2009 Sep 30.

DOI:10.1128/CVI.00294-09
PMID:19793897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2786378/
Abstract

Five commercially available enzyme-linked immunosorbent assays for the measurement of anti-tetanus toxoid immunoglobulin G (IgG) antibodies were evaluated for performance. The data suggest that there are manufacturer-dependent differences in sensitivity and accuracy for the determination of tetanus toxoid IgG antibodies that could result in different diagnostic interpretations.

摘要

对五种市售的用于检测抗破伤风类毒素免疫球蛋白G（IgG）抗体的酶联免疫吸附测定法进行了性能评估。数据表明，在测定破伤风类毒素IgG抗体时，不同厂家生产的检测方法在灵敏度和准确性方面存在差异，这可能导致不同的诊断解读。

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本文引用的文献

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Comparison of three enzyme-linked immunosorbent assays for detection of immunoglobulin g antibodies to tetanus toxoid with reference standards and the impact on clinical practice.三种酶联免疫吸附测定法检测破伤风类毒素免疫球蛋白G抗体与参考标准的比较及其对临床实践的影响。
Clin Vaccine Immunol. 2008 Dec;15(12):1751-4. doi: 10.1128/CVI.00254-08. Epub 2008 Oct 8.
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Cellular and humoral responses to tetanus vaccination in Gabonese children.加蓬儿童对破伤风疫苗接种的细胞和体液反应。
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A comparison of enzyme-linked immunosorbent assay (ELISA) with the toxin neutralization test in mice as a method for the estimation of tetanus antitoxin in human sera.酶联免疫吸附测定（ELISA）与小鼠毒素中和试验作为一种测定人血清中破伤风抗毒素方法的比较。
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