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五种市售抗破伤风类毒素免疫球蛋白G酶联免疫吸附测定法的比较。

Comparison of five commercial anti-tetanus toxoid immunoglobulin G enzyme-linked immunosorbent assays.

作者信息

Perry A L, Hayes A J, Cox H A, Alcock F, Parker A R

机构信息

The Binding Site Group Limited, P.O. Box 11712, Birmingham B14 4ZB, United Kingdom.

出版信息

Clin Vaccine Immunol. 2009 Dec;16(12):1837-9. doi: 10.1128/CVI.00294-09. Epub 2009 Sep 30.

Abstract

Five commercially available enzyme-linked immunosorbent assays for the measurement of anti-tetanus toxoid immunoglobulin G (IgG) antibodies were evaluated for performance. The data suggest that there are manufacturer-dependent differences in sensitivity and accuracy for the determination of tetanus toxoid IgG antibodies that could result in different diagnostic interpretations.

摘要

对五种市售的用于检测抗破伤风类毒素免疫球蛋白G(IgG)抗体的酶联免疫吸附测定法进行了性能评估。数据表明,在测定破伤风类毒素IgG抗体时,不同厂家生产的检测方法在灵敏度和准确性方面存在差异,这可能导致不同的诊断解读。

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本文引用的文献

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Diphtheria and tetanus toxoids.白喉和破伤风类毒素
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The fall-off in serum concentration of tetanus antitoxin after primary and booster vaccination.
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