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弥漫性特发性骨肥厚症并颈椎强直患者发生急性呼吸衰竭的两种不同病因。

Two different causes of acute respiratory failure in a patient with diffuse idiopathic skeletal hyperostosis and ankylosed cervical spine.

机构信息

Department of Orthopaedic Surgery, University Medical Centre Ljubljana, Zaloska cesta 9, 1000 Ljubljana, Slovenia.

出版信息

Eur Spine J. 2010 Jul;19 Suppl 2(Suppl 2):S130-4. doi: 10.1007/s00586-009-1159-6. Epub 2009 Oct 2.

Abstract

We report a case of 73-year-old man with massive hyperostosis of the cervical spine associated with diffuse idiopathic skeletal hyperostosis (DISH), resulting in dysphagia, hoarseness and acute respiratory insufficiency. An emergency operation was performed, which involved excision of osteophytes at the level of C6-C7, compressing the trachea against enlarged sternoclavicular joints, also affected by DISH. Approximately 3 years later, the patient sustained a whiplash injury in a low impact car accident, resulting in a C3-C4 fracture dislocation, which was not immediately diagnosed because he did not seek medical attention after the accident. For the next 6 months, he had constant cervical pain, which was growing worse and eventually became associated with dysphagia and dyspnoea, ending once again in acute respiratory failure due to bilateral palsy of the vocal cords. The patient underwent a second operation, which comprised partial reduction and combined anteroposterior fixation of the fractured vertebrae. Twenty months after the second operation, mild hoarseness was still present, but all other symptoms had disappeared. The clinical manifestations, diagnosis and treatment of the two unusual complications of DISH are discussed.

摘要

我们报告一例 73 岁男性,患有广泛的颈椎骨质增生症,伴有弥漫性特发性骨肥厚(DISH),导致吞咽困难、声音嘶哑和急性呼吸功能不全。紧急手术切除了 C6-C7 水平压迫气管的骨赘,胸骨锁骨关节也受到 DISH 影响。大约 3 年后,患者在一次低冲击汽车事故中遭受了挥鞭伤,导致 C3-C4 骨折脱位,但由于事故后未寻求医疗,未立即诊断。在接下来的 6 个月中,他一直有持续性的颈部疼痛,病情逐渐加重,最终出现吞咽困难和呼吸困难,再次因双侧声带瘫痪导致急性呼吸衰竭。患者接受了第二次手术,包括骨折椎体的部分复位和前后联合固定。第二次手术后 20 个月,仍存在轻度声音嘶哑,但所有其他症状均已消失。讨论了 DISH 两种罕见并发症的临床表现、诊断和治疗。

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本文引用的文献

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