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Genetic Influences on Alcoholism Risk: A Review of Adoption and Twin Studies.酒精成瘾风险的遗传影响:收养与双生子研究综述
Alcohol Health Res World. 1995;19(3):166-171.
2
Proceeding From Observed Correlation to Causal Inference: The Use of Natural Experiments.从观察相关性到因果推断:自然实验的应用。
Perspect Psychol Sci. 2007 Dec;2(4):377-95. doi: 10.1111/j.1745-6916.2007.00050.x.
3
Paternal alcoholism and offspring ADHD problems: a children of twins design.父亲酗酒与后代多动症问题:一项双胞胎子女设计研究
Twin Res Hum Genet. 2009 Feb;12(1):53-62. doi: 10.1375/twin.12.1.53.
4
Alcohol dependence and reproductive onset: findings in two Australian twin cohorts.酒精依赖与生殖起始:来自两个澳大利亚双胞胎队列的研究结果
Alcohol Clin Exp Res. 2008 Nov;32(11):1865-74. doi: 10.1111/j.1530-0277.2008.00771.x. Epub 2008 Sep 5.
5
Searching for an environmental effect of parental alcoholism on offspring alcohol use disorder: a genetically informed study of children of alcoholics.探寻父母酗酒对子女酒精使用障碍的环境影响:一项针对酗酒者子女的基因信息研究。
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6
Prevalence, correlates, disability, and comorbidity of DSM-IV alcohol abuse and dependence in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions.美国《精神疾病诊断与统计手册》第四版中酒精滥用与酒精依赖的患病率、相关因素、残疾情况及共病情况:酒精及相关疾病全国流行病学调查结果
Arch Gen Psychiatry. 2007 Jul;64(7):830-42. doi: 10.1001/archpsyc.64.7.830.
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Maternal alcohol use disorder and offspring ADHD: disentangling genetic and environmental effects using a children-of-twins design.母亲酒精使用障碍与后代注意力缺陷多动障碍:利用双胞胎子代设计解析遗传和环境影响。
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10
Revisiting the children of twins: can they be used to resolve the environmental effects of dyadic parental treatment on child behavior?重新审视双胞胎的子女:他们能否用于解析双亲二元治疗对儿童行为的环境影响?
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父母酗酒与子女行为问题:澳大利亚双胞胎子女的研究结果

Parental alcoholism and offspring behavior problems: findings in Australian children of twins.

作者信息

Waldron Mary, Martin Nicholas G, Heath Andrew C

机构信息

Department of Counseling and Educational Psychology, School of Education, Indiana University, Bloomington, IN 47405, United States of America.

出版信息

Twin Res Hum Genet. 2009 Oct;12(5):433-40. doi: 10.1375/twin.12.5.433.

DOI:10.1375/twin.12.5.433
PMID:19803771
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2891521/
Abstract

We examine the impact of rearing by an alcoholic parent on risk for child behavior problems using data on 2492 offspring drawn from two ongoing studies of children of female and male same- and opposite-sex twin pairs. Results of regression models predicting child behavior problems from parent and co-twin lifetime history of alcohol use disorder (AUD) provide support for genetic but not environmental transmission of externalizing and a measure of total problem behaviors. Results for internalizing behavior were inconclusive with respect to transmission of risk.

摘要

我们利用来自两项正在进行的针对女性和男性同卵及异卵双胞胎子女的研究中的2492名后代的数据,研究酗酒父母的养育方式对儿童行为问题风险的影响。从父母和双胞胎共同的酒精使用障碍(AUD)终生史预测儿童行为问题的回归模型结果,为外化行为和总体问题行为的遗传而非环境传递提供了支持。关于内化行为风险的传递,结果尚无定论。