Henrich T J, Marty F M, Milner D A, Thorner A R
Division of Infectious Diseases, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Transpl Infect Dis. 2009 Oct;11(5):458-62. doi: 10.1111/j.1399-3062.2009.00418.x.
We describe a woman with relapsed acute myelogenous leukemia after allogeneic stem cell transplantation who developed disseminated Geotrichum candidum infection during chemotherapy-induced neutropenia. The isolate was susceptible to voriconazole, amphotericin B, and micafungin in vitro. We review the literature regarding invasive infections with G. candidum, which predominantly affect immunocompromised hosts, and discuss potential therapies for this rare pathogen.
我们描述了一名异基因干细胞移植后复发的急性髓性白血病女性患者，她在化疗引起的中性粒细胞减少期间发生了播散性白吉利毛孢子菌感染。该分离株在体外对伏立康唑、两性霉素B和米卡芬净敏感。我们回顾了关于白吉利毛孢子菌侵袭性感染的文献，这种感染主要影响免疫功能低下的宿主，并讨论了针对这种罕见病原体的潜在治疗方法。
