Norwegian University of Science and Technology, Department of Circulation and Medical Imaging, Trondheim, Norway.
Int J Sports Med. 2009 Dec;30(12):872-8. doi: 10.1055/s-0029-1238292.
The aim of the present study was to investigate whether hyperoxic aerobic high intensity one-legged interval cycling improves peak oxygen uptake (V O (2peak)) compared to normoxic training in patients with severe chronic obstructive pulmonary disease, and to evaluate the acute effect of hyperoxia during one- and two-legged peak exercise testing. Twelve COPD patients were recruited to perform 3 training sessions per week for 8 weeks in hyperoxia (n=7) or normoxia (n=5). Each leg was trained 4x4 min at 85-95% of the one-legged peak heart rate. One-legged V O (2peak) increased in the hyperoxia and normoxia training groups by 24 and 15% (16.1(13.2)-20.0(11.3) and 17.4(15.1)-20.0(6.7) mL.kg (-1).min (-1)) respectively. The corresponding increases in V O (2peak) during two-legged testing were 14% in both groups (20.1(11.5)-22.9(10.6) and 18.8(8.5)-21.4(7.3) mL.kg (-1).min (-1)). There were no differences between groups from pre- to post-training. Nor were there any differences between acute hyperoxia and normoxia at the pre- or post-peak exercise test. One-legged aerobic high intensity interval cycling significantly increases V O (2peak) in COPD patients. However, breathing supplemental oxygen during training or testing does not appear to improve V O (2peak) above the level attained by breathing ambient air.
本研究旨在探讨高氧有氧高强度单腿间歇骑行是否比常氧训练更能提高严重慢性阻塞性肺疾病患者的峰值摄氧量（V O (2peak)），并评估急性高氧对单腿和双腿峰值运动测试的影响。招募了 12 名 COPD 患者，每周进行 3 次训练，每次训练 8 周，分别在高氧（n=7）或常氧（n=5）下进行。每条腿以 85-95%的单腿峰值心率进行 4x4 分钟的训练。高氧和常氧训练组的单腿 V O (2peak)分别增加了 24%和 15%（16.1(13.2)-20.0(11.3)和 17.4(15.1)-20.0(6.7)mL.kg (-1).min (-1)）。双腿测试中 V O (2peak)的相应增加分别为两组的 14%（20.1(11.5)-22.9(10.6)和 18.8(8.5)-21.4(7.3)mL.kg (-1).min (-1)）。从训练前到训练后，两组之间没有差异。在预峰值运动测试或后峰值运动测试中，急性高氧和常氧之间也没有差异。单腿有氧高强度间歇骑行显著增加 COPD 患者的 V O (2peak)。然而，在训练或测试中呼吸补充氧气似乎并不能使 V O (2peak)提高到呼吸环境空气时的水平之上。
