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Gestational choriocarcinoma diagnosed with spontaneous splenic rupture after pregnancy induced by in vitro fertilization: a case report.体外受精诱导妊娠后诊断为妊娠性绒毛膜癌并自发性脾破裂:一例报告
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Metastatic choriocarcinoma with spontaneous splenic rupture following term pregnancy: a case report.足月妊娠后发生自发性脾破裂的转移性绒毛膜癌:一例报告
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Ultra-high-risk choriocarcinoma with atraumatic splenic rupture: a rare case report.超高危绒毛膜癌致脾脏自发性破裂:1 例罕见病例报告。
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Laparoscopic splenectomy for splenic rupture secondary to metastatic choriocarcinoma.腹腔镜脾切除术治疗转移性绒毛膜癌继发脾破裂。
Ann Hepatobiliary Pancreat Surg. 2018 Feb;22(1):79-82. doi: 10.14701/ahbps.2018.22.1.79. Epub 2018 Feb 26.

本文引用的文献

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Is there a relationship between treatment for infertility and gestational trophoblastic disease?不孕症治疗与妊娠滋养细胞疾病之间存在关联吗?
Hum Reprod. 2004 Feb;19(2):365-7. doi: 10.1093/humrep/deh068.
2
Characteristics of ovarian and uterine cancers in a cohort of in vitro fertilization patients.一组体外受精患者的卵巢癌和子宫癌特征
Gynecol Oncol. 2001 Jul;82(1):64-8. doi: 10.1006/gyno.2001.6209.
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Ovarian tumors in a cohort of infertile women.一组不孕女性中的卵巢肿瘤。
N Engl J Med. 1994 Sep 22;331(12):771-6. doi: 10.1056/NEJM199409223311204.
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Fertility drugs and risk of epithelial ovarian cancer in Italy.
Hum Reprod. 1994 Sep;9(9):1673-5. doi: 10.1093/oxfordjournals.humrep.a138771.
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[Choriocarcinoma after in vitro fertilization].[体外受精后的绒毛膜癌]
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Risk factors for complete molar pregnancy from a case-control study.一项病例对照研究中完全性葡萄胎的危险因素。
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Choriocarcinoma of the fallopian tube associated with induced superovulation in an IVF program; a case report.体外受精程序中与诱导超排卵相关的输卵管绒毛膜癌;病例报告
Eur J Obstet Gynecol Reprod Biol. 1989 Nov;33(2):183-6. doi: 10.1016/0028-2243(89)90212-8.
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Androgenetic origin of hydatidiform mole.葡萄胎的雄激素起源。
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体外受精诱导妊娠后诊断为妊娠性绒毛膜癌并自发性脾破裂:一例报告

Gestational choriocarcinoma diagnosed with spontaneous splenic rupture after pregnancy induced by in vitro fertilization: a case report.

作者信息

Yürüyen Mehmet, Yildiz Ozcan, Papila Cigdem, Tuzuner Nukhet

机构信息

Department of Medical Oncology, Istanbul University, Cerrahpasa Medical Faculty, Kocamustafapasa, Turkey.

出版信息

Cases J. 2009 May 15;2:7518. doi: 10.1186/1757-1626-2-7518.

DOI:10.1186/1757-1626-2-7518
PMID:19829989
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2740022/
Abstract

Gestational choriocarcinoma is a highly malignant tumor of trophoblastic cells with a propensity to metastasize to various sites including lungs, vagina, brain, liver, kidney, and gastrointestinal tract, in descending order of frequency. A 29-year-old Caucasian woman presented to the hospital as an emergency with abdominal pain, hypotension, nausea and vomiting at about 6th month of a twin delivery after in vitro fertilization. Our case probably represents the first case of metastatic choriocarcinoma developed after in vitro fertilization, whether associted with or not, which was cured successfully after chemotherapy.

摘要

妊娠性绒毛膜癌是一种高度恶性的滋养层细胞肿瘤,容易转移至包括肺、阴道、脑、肝、肾和胃肠道等不同部位,转移频率依次递减。一名29岁的白种女性在体外受精后双胎分娩约6个月时因腹痛、低血压、恶心和呕吐作为急诊入院。我们的病例可能代表了首例体外受精后发生的转移性绒毛膜癌,无论是否与之相关,经化疗后成功治愈。