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体外受精诱导妊娠后诊断为妊娠性绒毛膜癌并自发性脾破裂:一例报告

Gestational choriocarcinoma diagnosed with spontaneous splenic rupture after pregnancy induced by in vitro fertilization: a case report.

作者信息

Yürüyen Mehmet, Yildiz Ozcan, Papila Cigdem, Tuzuner Nukhet

机构信息

Department of Medical Oncology, Istanbul University, Cerrahpasa Medical Faculty, Kocamustafapasa, Turkey.

出版信息

Cases J. 2009 May 15;2:7518. doi: 10.1186/1757-1626-2-7518.

Abstract

Gestational choriocarcinoma is a highly malignant tumor of trophoblastic cells with a propensity to metastasize to various sites including lungs, vagina, brain, liver, kidney, and gastrointestinal tract, in descending order of frequency. A 29-year-old Caucasian woman presented to the hospital as an emergency with abdominal pain, hypotension, nausea and vomiting at about 6th month of a twin delivery after in vitro fertilization. Our case probably represents the first case of metastatic choriocarcinoma developed after in vitro fertilization, whether associted with or not, which was cured successfully after chemotherapy.

摘要

妊娠性绒毛膜癌是一种高度恶性的滋养层细胞肿瘤,容易转移至包括肺、阴道、脑、肝、肾和胃肠道等不同部位,转移频率依次递减。一名29岁的白种女性在体外受精后双胎分娩约6个月时因腹痛、低血压、恶心和呕吐作为急诊入院。我们的病例可能代表了首例体外受精后发生的转移性绒毛膜癌,无论是否与之相关,经化疗后成功治愈。

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