Masoodi Ibrahim, Chalkoo Mushtaq, Rashid Arshad, Wani Imtiyaz A
Department of Medicine and 2Department of Surgery, Government Medical College, Srinagar, Kashmir 190010, India.
Cases J. 2009 May 11;2:7525. doi: 10.1186/1757-1626-2-7525.
Gastrointestinal stromal tumors are the commonest mesenchymal tumors of the gastrointestinal tract, the stomach and small intestine are the favored sites of occurrence. They rarely occur in the colon, rectum and esophagus. GIST is neoplasm of mesenchymal origin originating from precursors of the interstitial cells of cajal. The symptoms of gastrointestinal stromal tumor depend on the site and size of the tumor, and may include abdominal pain, gastrointestinal bleeding or signs of obstruction; small tumors may, however, be asymptomatic. Majority of the patients with gastrointestinal stromal tumor have bloody stools and abdominal pain as the commonest manifestation. We describe a young female with extra luminal colonic gastrointestinal stromal tumor presenting as mass abdomen.
We describe 34-year-old female from north Indian state of Jammu and Kashmir who had presented with history of slowly increasing epigastric lump associated with abdominal discomfort of 4 months duration. She had no features of luminal obstruction. Her contrast enhanced computed tomography abdomen revealed a large extra-colonic mass in relation to transverse colon. The tumor was resected and histology was suggestive of gastrointestinal stromal tumor.
Extra luminal colonic gastrointestinal stromal tumors are very rare and can present as mass abdomen. Resection is the treatment of choice.
胃肠道间质瘤是胃肠道最常见的间叶组织肿瘤,胃和小肠是其好发部位。它们很少发生于结肠、直肠和食管。胃肠道间质瘤是起源于卡哈尔间质细胞前体的间叶组织肿瘤。胃肠道间质瘤的症状取决于肿瘤的部位和大小,可能包括腹痛、胃肠道出血或梗阻迹象;然而,小肿瘤可能无症状。大多数胃肠道间质瘤患者以便血和腹痛为最常见表现。我们描述了一名年轻女性,其腔外结肠胃肠道间质瘤表现为腹部肿块。
我们描述了一名来自印度北部查谟和克什米尔邦的34岁女性,她有上腹部肿块缓慢增大并伴有4个月腹部不适的病史。她没有管腔梗阻的特征。她的腹部增强计算机断层扫描显示横结肠处有一个大的结肠外肿块。肿瘤被切除,组织学检查提示为胃肠道间质瘤。
腔外结肠胃肠道间质瘤非常罕见,可表现为腹部肿块。手术切除是首选治疗方法。