Mazmanian Sarkis K
Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.
Immunity. 2009 Oct 16;31(4):536-8. doi: 10.1016/j.immuni.2009.09.005.
Microbes appear to modulate homeostatic plasticity of T helper and T regulatory cells. In this issue of Immunity, Gaboriau-Routhiau et al. (2009) now reveal that segmented filamentous bacteria uniquely coordinate the intestinal T cell profile. The potential implications of this process to various immune functions are discussed.
微生物似乎可调节辅助性T细胞和调节性T细胞的稳态可塑性。在本期《免疫》杂志中,加博里奥 - 鲁蒂奥等人(2009年)现已揭示,分节丝状细菌独特地协调肠道T细胞谱。本文讨论了这一过程对各种免疫功能的潜在影响。