Faoussi Mohamed, Bounou Salim, Wahbi Mohammed
Euromed Research Center, BiomedTech Engineering School, University EUROMED de Fès, Fez, Morocco.
Systems Engineering Laboratory, The Intelligent Systems and Sensor Networks team, EHTP, Casablanca Morocco.
J Biomed Phys Eng. 2024 Apr 1;14(2):199-208. doi: 10.31661/jbpe.v0i0.2304-1612. eCollection 2024 Apr.
This study presents a mechanical model of a novel medical device designed to optimize the osseointegration process in upper and lower limb amputees, leading to the promotion of optimal rehabilitation. The medical device is developed to reduce the risk of implant failure, leading to re-amputation above the implant. The proposed model serves several purposes: 1) to guide the osseointegration process by providing electrical endo-stimulation directly to the bone-implant contact site, using an invasive electrical stimulation system, which is implanted in the bone permanently, 2) to locally transmit stem cells after implantation, without the need for opening the skin or perforating the bone, which is particularly useful for regenerative medicine after partial healing of the implant, 3) to transmit necessary nutrients from the bone, also without opening the skin or puncturing the bone, and 4) to combat infections by locally administering drugs after implantation.
本研究提出了一种新型医疗设备的力学模型，该设备旨在优化上肢和下肢截肢者的骨整合过程，从而促进最佳康复。开发该医疗设备是为了降低植入物失效的风险，避免在植入物上方再次截肢。所提出的模型有几个用途：1）通过使用永久植入骨内的侵入性电刺激系统，直接向骨 - 植入物接触部位提供电内刺激，以引导骨整合过程；2）在植入后局部传输干细胞，无需切开皮肤或穿透骨头，这对于植入物部分愈合后的再生医学特别有用；3）同样无需切开皮肤或穿刺骨头，从骨中传输必要的营养物质；4）在植入后通过局部给药来对抗感染。
