Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, Wuhan, PR China.
Bioelectrochemistry. 2010 Aug;79(1):1-5. doi: 10.1016/j.bioelechem.2009.09.011. Epub 2009 Oct 2.
A carbon-coated nickel magnetic nanoparticles modified glassy carbon electrode (C-Ni/GCE) was fabricated. The carbon-coated nickel magnetic nanoparticles were characterized with transmission electron microscopy (TEM). The electrochemical behaviors of norepinephrine (NE) were investigated on the modified electrode by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The carbon-coated nickel magnetic nanoparticles showed excellent electrocatalytic activity for the electrochemical redox of NE. NE exhibited two couples of well-defined redox peaks on C-Ni/GCE over the potential range from -0.4 to 0.8V in phosphate buffer solution (PBS) (pH=7.0). The redox mechanism for NE was proposed. DPV response of NE on the C-Ni/GCE showed that the catalytic oxidative peak current was linear with the square root concentration of NE in the range of 2.0 x 10(-7) to 8.0 x 10(-5)M, with a detection limit of 6.0 x 10(-8)M. The C-Ni/GCE showed good sensitivity, selectivity and stability for the determination of NE.
制备了一种碳包覆镍磁性纳米粒子修饰的玻碳电极（C-Ni/GCE）。用透射电子显微镜（TEM）对碳包覆镍磁性纳米粒子进行了表征。通过循环伏安法（CV）和差分脉冲伏安法（DPV）研究了修饰电极上去甲肾上腺素（NE）的电化学行为。碳包覆镍磁性纳米粒子对 NE 的电化学氧化还原表现出优异的电催化活性。在磷酸盐缓冲溶液（PBS）（pH=7.0）中，NE 在 C-Ni/GCE 上的电位范围为-0.4 至 0.8V 时，呈现出两对定义良好的氧化还原峰。提出了 NE 的氧化还原机制。C-Ni/GCE 上 NE 的 DPV 响应表明，催化氧化峰电流与 NE 的浓度的平方根在 2.0 x 10(-7) 至 8.0 x 10(-5)M 的范围内呈线性关系，检测限为 6.0 x 10(-8)M。C-Ni/GCE 对 NE 的测定具有良好的灵敏度、选择性和稳定性。
