孟加拉国高校教职工和学生血脂异常的患病率及其相关因素分析。

Prevalence of dyslipidemia and its associated factors among university academic staff and students in Bangladesh.

机构信息

Department of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, 3114, Bangladesh.

出版信息

BMC Cardiovasc Disord. 2023 Jul 21;23(1):366. doi: 10.1186/s12872-023-03399-1.

DOI:10.1186/s12872-023-03399-1

PMID:37479968

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10362587/

Abstract

BACKGROUND

Dyslipidemia is one of the important contributors to cardiovascular disease and type 2 diabetes. There is little or no information on dyslipidemia among academic staff and students in Bangladesh. Therefore, this study aimed to investigate the prevalence and factors related to dyslipidemia among university academic staff and students in Bangladesh.

METHODS

A total of 533 participants (302 academic staff and 231 students) were enrolled in this cross-sectional study. A simple random sampling technique was used to enrol the participants. Fasting blood samples were obtained from the participants, and serum levels of triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were measured using the standard methods. Dyslipidemia was defined according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP-III) model guideline. Multivariable logistic regression was conducted to identify the factors related to lipid marker abnormalities.

RESULTS

Overall, the prevalence of dyslipidemia was 81.5%, of which 85% was in staff and 76.5% in students. A significant difference was found in the prevalence of dyslipidemia between males and females only in the student group (p < 0.01). Among staff, hypertriglyceridemia prevalence was 49.7%, hypercholesterolemia 23%, high LDL-C 24.7% and low HDL-C 77.3%. On the other hand, hypertriglyceridemia prevalence was 39%, hypercholesterolemia 25.6%, high LDL-C 26.5% and low HDL-C 69.3% among students. The most common lipid abnormality was low HDL-C in both groups. The prevalence of mixed dyslipidemia was 14.2% and 14.1% in staff and students, respectively. According to the regression analysis, increased age, obesity, diabetes, and inadequate physical activity were significantly associated with dyslipidemia.

CONCLUSIONS

Dyslipidemia was prevalent among the majority of the study participants. Increased age, obesity, diabetes, and inadequate physical activity were significantly associated with dyslipidemia. The study's results highlight the importance of implementing interventions to address the associated risk factors of dyslipidemia among academic staff and students in Bangladesh.

摘要

背景

血脂异常是心血管疾病和 2 型糖尿病的重要致病因素之一。孟加拉国的学术人员和学生中血脂异常的信息很少或没有。因此，本研究旨在调查孟加拉国大学学术人员和学生血脂异常的患病率及相关因素。

方法

本横断面研究共纳入 533 名参与者（302 名教职工和 231 名学生）。采用简单随机抽样技术招募参与者。从参与者中抽取空腹血样，采用标准方法检测血清三酰甘油（TG）、总胆固醇（TC）、高密度脂蛋白胆固醇（HDL-C）和低密度脂蛋白胆固醇（LDL-C）水平。血脂异常根据国家胆固醇教育计划成人治疗专家组第三版（NCEP-ATP-III）模型指南进行定义。采用多变量逻辑回归分析确定与血脂标志物异常相关的因素。

结果

总体而言，血脂异常的患病率为 81.5%，其中 85%为教职工，76.5%为学生。仅在学生组中，男性和女性的血脂异常患病率存在显著差异（p<0.01）。教职工中，高甘油三酯血症患病率为 49.7%，高胆固醇血症为 23%，高 LDL-C 血症为 24.7%，低 HDL-C 血症为 77.3%。另一方面，学生中高甘油三酯血症患病率为 39%，高胆固醇血症为 25.6%，高 LDL-C 血症为 26.5%，低 HDL-C 血症为 69.3%。两组中最常见的血脂异常是低 HDL-C。混合性血脂异常的患病率分别为教职工 14.2%和学生 14.1%。根据回归分析，年龄增长、肥胖、糖尿病和体力活动不足与血脂异常显著相关。