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MR-PET 的现状、挑战与展望。

The current state, challenges and perspectives of MR-PET.

机构信息

Institute of Neuroscience and Medicine-4, Forschungszentrum Jülich, 52425 Jülich, Germany.

出版信息

Neuroimage. 2010 Feb 1;49(3):2072-82. doi: 10.1016/j.neuroimage.2009.10.036. Epub 2009 Oct 21.

Abstract

Following the success of PET/CT during the last decade and the recent increasing proliferation of SPECT/CT, another hybrid imaging instrument has been gaining more and more interest: MR-PET. First combined, simultaneous PET and MR studies carried out in small animals demonstrated the feasibility of the new approach. Concurrently, some prototypes of an MR-PET scanner for simultaneous human brain studies have been built, their performance is being tested and preliminary applications have already been shown. Through this pioneering work, it has become clear that advances in the detector design are necessary for further optimization. Recently, the different issues related to the present state and future prospects of MR-PET were presented and discussed during an international 2-day workshop at the Forschungszentrum Jülich, Germany, held after, and in conjunction with, the 2008 IEEE Nuclear Science Symposium and Medical Imaging Conference in Dresden, Germany on October 27-28, 2008. The topics ranged from small animal MR-PET imaging to human MR-BrainPET imaging, new detector developments, challenges/opportunities for ultra-high field MR-PET imaging and considerations of possible future research and clinical applications. This report presents a critical summary of the contributions made to the workshop.

摘要

在过去十年 PET/CT 的成功以及最近 SPECT/CT 的日益普及之后,另一种混合成像仪器越来越受到关注:MR-PET。最初在小动物中进行的同时进行的 PET 和 MR 联合研究证明了这种新方法的可行性。同时,已经构建了一些用于同时进行人脑研究的 MR-PET 扫描仪原型,正在对其性能进行测试,并已经展示了初步的应用。通过这项开创性的工作,人们清楚地认识到,探测器设计的进步对于进一步优化是必要的。最近,在德国于利希研究中心举行的为期两天的国际研讨会上,对当前状态和未来前景的 MR-PET 相关的不同问题进行了介绍和讨论,该研讨会是在 2008 年 10 月 27 日至 28 日在德国德累斯顿举行的 2008 年 IEEE 核科学研讨会和医学成像会议之后举行的。主题范围从小动物的 MR-PET 成像到人类的 MR-BrainPET 成像、新型探测器的开发、超高磁场 MR-PET 成像的挑战/机遇以及对未来可能的研究和临床应用的考虑。本报告批判性地总结了研讨会的贡献。

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