Ang Darwin N, Rivara Frederick P, Nathens Avery, Jurkovich Gregory J, Maier Ronald V, Wang Jin, MacKenzie Ellen J
Department of Surgery, University of Washington, Seattle, WA.
J Am Coll Surg. 2009 Nov;209(5):595-602. doi: 10.1016/j.jamcollsurg.2009.08.003. Epub 2009 Sep 19.
The goal of this study was to examine the association between patient complications and admission to Level I trauma centers (TC) compared with nontrauma centers (NTC).
This was a retrospective cohort study of data derived from the National Study on the Costs and Outcomes of Trauma (NSCOT). Patients were recruited from 18 Level I TCs and 51 NTCs in 15 regions encompassing 14 states. Trained study nurses, using standardized forms, abstracted the medical records of the patients. The overall number of complications per patient was identified, as was the presence or absence of 13 specific complications.
Patients treated in TCs were more likely to have any complication compared with patients in NTCs, with an adjusted relative risk (RR) of 1.34 (95% CI, 1.03, 1.74). For individual complications, only the urinary tract infection RR of 1.94 (95% CI, 1.07, 3.17) was significantly higher in TCs. TC patients were more likely to have 3 or more complications (RR, 1.83; 95% CI, 1.16, 2.90). Treatment variables that are surrogates for markers of injury severity, such as use of pulmonary artery catheters, multiple operations, massive transfusions (> 2,500 mL packed red blood cells), and invasive brain catheters, occurred significantly more often in TCs.
Trauma centers have a slightly higher incidence rate of complications, even after adjusting for patient case mix. Aggressive treatment may account for a significant portion of TC-associated complications. Pulmonary artery catheter use and intubation had the most influence on overall TC complication rates. Additional study is needed to provide accurate benchmark measures of complication rates and to determine their causes.
本研究的目的是检验与非创伤中心(NTC)相比,一级创伤中心(TC)收治患者的并发症情况。
这是一项基于创伤成本与结果国家研究(NSCOT)数据的回顾性队列研究。患者来自14个州15个地区的18个一级创伤中心和51个非创伤中心。经过培训的研究护士使用标准化表格提取患者的病历。确定每位患者的并发症总数以及13种特定并发症的有无。
与非创伤中心的患者相比,创伤中心治疗的患者出现任何并发症的可能性更高,校正相对风险(RR)为1.34(95%CI,1.03,1.74)。对于个别并发症,仅创伤中心的尿路感染RR为1.94(95%CI,1.07,3.17)显著更高。创伤中心的患者更有可能出现3种或更多并发症(RR,1.83;95%CI,1.16,2.90)。作为损伤严重程度标志物替代指标的治疗变量,如使用肺动脉导管、多次手术、大量输血(>2500毫升浓缩红细胞)和有创脑导管,在创伤中心出现的频率显著更高。
即使对患者病例组合进行调整后,创伤中心的并发症发生率仍略高。积极的治疗可能是创伤中心相关并发症的重要原因。肺动脉导管的使用和插管对创伤中心总体并发症发生率影响最大。需要进一步研究以提供准确的并发症发生率基准指标并确定其原因。