New England Research Institutes, Watertown, Massachusetts 02111, USA.
Urology. 2010 Jan;75(1):27-33. doi: 10.1016/j.urology.2009.08.019. Epub 2009 Oct 24.
To investigate the relationship between the severity of urine leakage and quality of life (QOL) in men and women of different race/ethnicity.
An epidemiologic survey was conducted with a population-based random sample of 3202 women and 2301 men (1767 black, 1877 Hispanic, 1859 white) aged 30-79 years in Boston, MA. Severity of leakage was based on frequency and amount by the Sandvik Severity Scale. QOL was measured with physical and mental component summaries of Medical Outcomes Study Short Form-12. Covariates included race/ethnicity, age, socioeconomic status, urinary incontinence risk factors, and comorbidities. Analysis included multivariate linear regression modeling by gender.
Urine leakage, most of which was mild or moderate, was reported in 30% of women and 18% of men. Women (5.1%) were more likely than men (0.9%) to report severe leakage. In multivariate analysis, as severity of leakage increased, both components of QOL declined, with decreases in scores of 7-8 points for men (P < or = .001 for each) and 4-6 points (P < .05 and P = .001, respectively) for women. Severe leakage was associated with a greater decline in QOL than that observed for most other comorbidities considered. The effect of urine leakage on QOL was similar among racial and ethnic groups.
Urine leakage impairs QOL for both men and women, with no evidence of different effects by racial/ethnic group. Leakage has clinically significant effects on physical health-related QOL for men and on mental health QOL for both men and women.
调查不同种族/民族的男性和女性尿失禁严重程度与生活质量(QOL)之间的关系。
对马萨诸塞州波士顿市的一个基于人群的随机样本进行了一项流行病学调查,共纳入 3202 名女性和 2301 名年龄在 30-79 岁的男性(1767 名黑人、1877 名西班牙裔、1859 名白人)。尿失禁严重程度基于 Sandvik 严重程度量表的频率和量进行评估。QOL 采用医疗结局研究简明健康状况量表 12 项的生理和心理成分综合得分进行测量。协变量包括种族/民族、年龄、社会经济地位、尿失禁风险因素和合并症。分析包括按性别进行的多变量线性回归建模。
30%的女性和 18%的男性报告有尿失禁,其中大多数为轻度或中度。女性(5.1%)比男性(0.9%)更有可能报告严重尿失禁。在多变量分析中,随着尿失禁严重程度的增加,QOL 的两个组成部分均下降,男性的评分下降 7-8 分(各 P<0.001),女性的评分下降 4-6 分(P<0.05 和 P=0.001)。与大多数其他考虑的合并症相比,严重尿失禁与 QOL 的下降更为相关。尿失禁对 QOL 的影响在不同种族和民族群体中相似。
尿失禁会降低男性和女性的 QOL,且无证据表明不同种族/民族之间的影响存在差异。尿失禁对男性的身体健康相关 QOL 以及对男性和女性的心理健康 QOL 均有明显的临床影响。