Department of Psychiatry, Kaohsiung Kai-Suan Psychiatric Hospital, Kaohsiung, Taiwan.
Kaohsiung J Med Sci. 2009 Nov;25(11):608-12. doi: 10.1016/S1607-551X(09)70564-9.
Changes in moods are one of the comorbid psychiatric manifestations that frequently occur in patients with Tourette's syndrome. The assessment of a manic episode in children with Tourette's syndrome is challenging. Furthermore, the treatment of children with comorbid mania and Tourette's syndrome has not been extensively studied. We present a 10-year-old boy who suffered from both Tourette's syndrome and mania, whose symptoms improved after using lithium and risperidone. The child was diagnosed with Tourette's syndrome at 7 years of age when he suffered from tics and experienced his first manic episode. He received monotherapy, including haloperidol, risperidone and aripiprazole, and the response was poor. When the combination of lithium and risperidone was used, the tics and mania subsided. It is important to assess individuals with Tourette's syndrome for associated bipolar disorder. The treatment of children with both disorders is a major clinical issue, and our case may serve as an example for successful treatment strategies.
情绪变化是抽动秽语综合征患者经常出现的合并精神科表现之一。评估抽动秽语综合征儿童的躁狂发作具有挑战性。此外，合并躁狂和抽动秽语综合征的儿童的治疗尚未得到广泛研究。我们介绍了一名 10 岁男孩，他同时患有抽动秽语综合征和躁狂症，在使用锂和利培酮后症状有所改善。这名儿童在 7 岁时被诊断为抽动秽语综合征，当时他患有抽搐，并经历了第一次躁狂发作。他接受了包括氟哌啶醇、利培酮和阿立哌唑在内的单药治疗，但反应不佳。当使用锂和利培酮联合治疗时，抽动和躁狂症状得到缓解。评估抽动秽语综合征患者是否存在相关的双相情感障碍很重要。两种疾病的儿童治疗是一个主要的临床问题，我们的病例可能为成功的治疗策略提供了一个范例。
