Laboratories of The Rockefeller Institute for Medical Research, New York.
J Exp Med. 1912 Mar 1;15(3):287-91. doi: 10.1084/jem.15.3.287.
Since guinea pig bone marrow and lymph gland cultivated for five days with goat blood generate substances that are hemolytic for goat red blood corpuscles, it can be concluded that tissues living outside of the organism react against an antigen by the production of an antibody.
豚鼠骨髓和五天龄的豚鼠淋巴结与羊血共同培养会产生使羊红细胞发生溶血的物质,这表明活的组织对外来抗原产生抗体是通过产生一种物质来实现的。