Department of Medicine, Stanford University Medical School, San Francisco.
J Exp Med. 1931 Feb 28;53(3):317-24. doi: 10.1084/jem.53.3.317.
Following the removal of half of the spleen in young adult rats there is a compensatory enlargement of the remaining portion of about 50 per cent while in mature rabbits no such compensatory hypertrophy follows a similar procedure. It is uncertain whether this difference is due to a difference in the function of the spleen in the two species or to the fact that the rats were infected with Bartonella muris while the rabbits were not.
幼年大鼠脾脏切除一半后,剩余部分会代偿性增大约 50%,而成熟兔在进行类似手术后则不会出现这种代偿性肥大。这种差异是由于两种物种脾脏功能不同,还是由于大鼠感染了伯氏疏螺旋体而兔子没有感染,目前尚不确定。