Hospital of The Rockefeller Institute for Medical Research.
J Exp Med. 1935 Jan 1;61(1):139-48. doi: 10.1084/jem.61.1.139.
On feeding to splenectomized dogs a diet producing black tongue, severe anemia developed associated with the presence of small bodies in or on the erythrocytes. The bodies were morphologically similar to Bartonella muris and Bartonella canis. The addition of lean beef to the diet, a material prophylactic against its effects, was followed by improvement of the blood levels, the presence of increased numbers of reticulocytes in the circulating blood, and the disappearance of the bodies. When the blood containing Bartonella-like bodies was injected into other splenectomized dogs fed a normal or a black tongue-producing diet, anemia developed in them and the bodies appeared in large numbers. Similar injections into non-splenectomized animals fed in the same way had anemia alone as its result. Injections into normal animals fed a normal diet caused not even anemia.
给行脾切除术的狗喂食一种可导致黑舌病的饮食后，会出现严重贫血，并伴有红细胞内或表面存在小体。这些小体在形态上与伯氏疏螺旋体和犬巴尔通体相似。在饮食中添加精瘦牛肉（对其有预防作用的物质）后，血液水平得到改善，循环血液中网织红细胞数量增加，小体消失。当含有类似伯氏疏螺旋体的血液被注入其他行脾切除术的狗，这些狗喂食正常饮食或可导致黑舌病的饮食，它们会出现贫血，并且会出现大量的小体。以同样方式喂食的非脾切除术动物，类似注射仅导致贫血。将其注入正常饮食的正常动物甚至不会引起贫血。
