Institut de Biologie Physico-Chimique, CNRS UPR 9073, 13 rue Pierre et Marie Curie, 75005 Paris, France.
J Bacteriol. 2010 Jan;192(1):356-9. doi: 10.1128/JB.01096-09.
23S rRNA maturation in Bacillus subtilis is catalyzed by the recently characterized enzyme Mini-RNase-III. Mini-III is dispensable, however, and 23S rRNA is matured by other ribonucleases in strains lacking this enzyme. Here we show that these RNases are the 5'-to-3' exoribonuclease RNase J1 and the 3'-to-5' exoribonucleases, principally RNase PH and YhaM.
枯草芽孢杆菌 23S rRNA 的成熟由最近鉴定的酶 Mini-RNase-III 催化。然而,Mini-III 是可有可无的,并且在缺乏这种酶的菌株中,23S rRNA 由其他核糖核酸酶成熟。在这里,我们表明这些核糖核酸酶是 5'-到-3'外切核糖核酸酶 RNase J1 和 3'-到-5'外切核糖核酸酶,主要是 RNase PH 和 YhaM。