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伴有皮肤转移性结核脓肿和多灶性骨结核。

Concomitant cutaneous metastatic tuberculous abscesses and multifocal skeletal tuberculosis.

作者信息

Sezgin Betul, Atilganoglu Ulviye, Yigit Ozgul, Ergün Selma Sönmez, Cambaz Nevin, Demirkesen Cuyan

机构信息

Department of Pediatry, Cerrahpasa Medical School, Istanbul, Turkey.

出版信息

Indian J Dermatol. 2008;53(3):149-53. doi: 10.4103/0019-5154.43208.

Abstract

Tuberculosis, one of the oldest diseases known to affect humans is caused by the bacteria mycobacterium tuberculosis. The disease usually affects the lungs, although, in up to one third of cases, other organs are involved. Metastatic tuberculosis abscess is a rare form of skin tuberculosis. It is characterized by nodule and abscess formation throughout the body after hematogenous spread of mycobacterium tuberculosis from a primary focus during a period of impaired immunity. Tuberculosis osteomyelitis is also a rare form of extrapulmonary tuberculosis in pediatric age group. Skeletal tuberculosis pathogenesis is related to reactivation of hematogenous foci or spread from adjacent paravertebral lymph nodes. Weight-bearing joints are affected most commonly. Bilateral hand and foot bone involvement is rarely reported. We present a five-year-old girl with two very rare presentations of the disease such as osteomyelitis and metastatic skin abscess.

摘要

结核病是已知影响人类最古老的疾病之一,由结核分枝杆菌引起。该病通常影响肺部,不过,在多达三分之一的病例中,其他器官也会受累。转移性结核脓肿是皮肤结核的一种罕见形式。它的特征是在免疫力受损期间,结核分枝杆菌从原发性病灶经血行播散至全身后形成结节和脓肿。结核性骨髓炎在儿童年龄组中也是一种罕见的肺外结核形式。骨骼结核的发病机制与血源性病灶的重新激活或来自相邻椎旁淋巴结的扩散有关。负重关节最常受累。双侧手足骨受累的情况很少有报道。我们报告了一名5岁女孩,患有该疾病两种非常罕见的表现,即骨髓炎和转移性皮肤脓肿。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aa0/2763739/c99732b01321/IJD-53-149-g001.jpg

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