Department of Biomedical Engineering, Case Western Reserve University, Cleveland OH, USA.
J Neural Eng. 2009 Dec;6(6):066005. doi: 10.1088/1741-2560/6/6/066005. Epub 2009 Nov 9.
Evaluation of the Case Western Reserve University spiral nerve cuff electrode on the femoral nerve trunk was performed intraoperatively in four subjects undergoing femoral-popliteal bypass surgery. The threshold, nerve size and selective activation capabilities of the electrode were examined. The activation thresholds for the first muscle to be recruited were 6.3, 9, 10.6, and 37.4 nC with pulse amplitudes ranging from 0.3 to 1 mA. The femoral nerve was found to have an elliptical cross-section with a major axis average length of 9 mm (8-12 mm) and a minor axis length of 1.5 mm. In all four subjects selective activation of the sartorius was obtained. In two subjects, the rectus femoris could also be selectively activated and in one subject the vastus medialis was selectively activated. Each electrode had four independent contacts that were evaluated separately. Small air bubbles were formed in the space over some contacts, preventing stimulation. This occurred in one contact in each electrode, leaving three effective stimulation channels. This issue has been corrected for future studies.
对在接受股-腘旁路手术的 4 名受试者的股神经干进行了凯斯西储螺旋神经袖套电极的术中评估。检查了电极的阈值、神经大小和选择性激活能力。第一个被募集的肌肉的激活阈值分别为 6.3、9、10.6 和 37.4nC，脉冲幅度范围为 0.3 至 1mA。股神经呈椭圆形横截面，长轴平均长度为 9mm（8-12mm），短轴长度为 1.5mm。在所有 4 名受试者中，均获得了缝匠肌的选择性激活。在 2 名受试者中，还可以选择性地激活股直肌，在 1 名受试者中可以选择性地激活股内侧肌。每个电极有四个独立的接触点，分别进行评估。一些接触点上方形成了小气泡，阻碍了刺激。这种情况在每个电极的一个接触点中发生，留下了三个有效的刺激通道。这个问题已经在未来的研究中得到纠正。
