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孟加拉国农村人口的葡萄糖耐量

Glucose tolerance in a rural population of Bangladesh.

作者信息

Rahim M A, Khan A K Azad, Ali S M K, Nahar Q, Shaheen A, Hussain A

出版信息

Int J Diabetes Dev Ctries. 2008 Apr;28(2):45-50. doi: 10.4103/0973-3930.43098.

DOI:10.4103/0973-3930.43098
PMID:19902047
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2772011/
Abstract

CONTEXT

The prevalence of type 2 diabetes is increasing in the Bangladeshi population. However, there is little information available on the prevalence of glucose intolerance, ie, type 2 diabetes, impaired glucose tolerance, and impaired fasting glucose.

AIMS

The main aim of this study is to determine the prevalence of different categories of glucose intolerance and their relationship with different anthropometric and demographic characteristics.

SETTINGS AND DESIGN

This cross-sectional study was performed in a rural area of Bangladesh.

MATERIALS AND METHODS

A random sample of 5000 persons aged >/= 20 years was included in this study. Fasting blood glucose was measured in 3981 individuals and 2-h post-glucose blood glucose was measured in 3954 subjects after the known cases of diabetes (n = 27) were excluded. Height, weight, waist and hip circumference, and blood pressure were measured.

STATISTICAL ANALYSIS

Pearson Chi-squared test and correlation test were used for analysis as appropriate.

RESULTS

The prevalence of impaired fasting glucose (IFG), impaired glucose tolerance (IGT) and diabetes (DM) were 1.3, 2.0, and 7.0%, respectively. IFG, IGT, and IFG + IGT were more prevalent in females. Age showed a significant positive relationship with increasing levels of glucose intolerance. Body mass index, waist circumference, and waist-to-hip ratio were higher in the glucose-intolerant group than in the normal glucose tolerance (NGT) group. There was a positive correlation between FBG and 2-h BG in NGT and DM subjects.

CONCLUSION

The FBG value identified more people with glucose intolerance than the 2-h BG. These findings will help developing diabetes preventive strategy in rural populations.

摘要

背景

孟加拉国人群中2型糖尿病的患病率正在上升。然而,关于葡萄糖耐量异常(即2型糖尿病、糖耐量受损和空腹血糖受损)患病率的信息却很少。

目的

本研究的主要目的是确定不同类型葡萄糖耐量异常的患病率及其与不同人体测量学和人口统计学特征的关系。

研究地点和设计

本横断面研究在孟加拉国的一个农村地区进行。

材料和方法

本研究纳入了5000名年龄≥20岁的随机样本。在排除已知糖尿病病例(n = 27)后,对3981名个体测量空腹血糖,对3954名受试者测量葡萄糖负荷后2小时血糖。测量身高、体重、腰围和臀围以及血压。

统计分析

酌情使用Pearson卡方检验和相关性检验进行分析。

结果

空腹血糖受损(IFG)、糖耐量受损(IGT)和糖尿病(DM)的患病率分别为1.3%、2.0%和7.0%。IFG、IGT和IFG + IGT在女性中更为普遍。年龄与葡萄糖耐量异常水平的升高呈显著正相关。葡萄糖耐量异常组的体重指数、腰围和腰臀比高于正常糖耐量(NGT)组。在NGT和DM受试者中,空腹血糖与2小时血糖之间存在正相关。

结论

空腹血糖值比2小时血糖检测出更多葡萄糖耐量异常的人。这些发现将有助于制定农村人群的糖尿病预防策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d4/2772011/ab21e290235d/IJDDC-28-45-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d4/2772011/b2fadbb62a5a/IJDDC-28-45-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d4/2772011/ab21e290235d/IJDDC-28-45-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d4/2772011/b2fadbb62a5a/IJDDC-28-45-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14d4/2772011/ab21e290235d/IJDDC-28-45-g002.jpg

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