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患有乳糜泻的儿童高脂肪摄入量。

High fat consumption in children with celiac disease.

作者信息

Ferrara P, Cicala M, Tiberi E, Spadaccio C, Marcella L, Gatto A, Calzolari P, Castellucci G

机构信息

Department of Pediatric Sciences, Università Cattolica Sacro Cuore, Rome, Italy.

出版信息

Acta Gastroenterol Belg. 2009 Jul-Sep;72(3):296-300.

Abstract

AIM

The purpose of this study was to estimate the caloric intake and fat consumption in children with celiac disease (CD) following a gluten-free diet (GFD).

PATIENTS AND METHODS

This study enrolled 100 subjects, including 50 children with CD on a gluten-free diet and a control group of 50 healthy children. Statistical analysis to compare groups was performed using one-way ANOVA.

RESULTS

A significant increase in fat consumption was observed in children with CD as compared to healthy children. The daily fat intake was 72.5 +/- 37.2 g per 100 g of food in the CD group and 52.9 +/- 35.4 g per 100 g of food in the control group (p < 0.008). A significant difference in fat intake was found between celiac and healthy females (10.21 +/- 3.15 g/100 g in the celiac group vs 7.46 +/- 2.91 g/100 g in the control group), p = 0.004.

CONCLUSIONS

This study describes a significantly higher fat consumption in patients with CD on GFD as compared to controls. This increase was more pronounced in females and during the puberal age. Based on these interesting preliminary results we estimate that further investigations are necessary, such as a randomized multicentre study on the long-term effects of GFD with particular attention to the imbalance in daily fat intake.

摘要

目的

本研究旨在评估采用无麸质饮食(GFD)的乳糜泻(CD)患儿的热量摄入和脂肪消耗情况。

患者与方法

本研究纳入了100名受试者,包括50名采用无麸质饮食的CD患儿以及由50名健康儿童组成的对照组。使用单因素方差分析进行组间比较的统计分析。

结果

与健康儿童相比,观察到CD患儿的脂肪消耗显著增加。CD组每100克食物的每日脂肪摄入量为72.5±37.2克,对照组为52.9±35.4克/100克食物(p<0.008)。乳糜泻女性与健康女性之间的脂肪摄入量存在显著差异(乳糜泻组为10.21±3.15克/100克,对照组为7.46±2.91克/100克),p=0.004。

结论

本研究表明,采用GFD的CD患者的脂肪消耗显著高于对照组。这种增加在女性以及青春期更为明显。基于这些有趣的初步结果,我们估计有必要进行进一步研究,例如关于GFD长期影响的随机多中心研究,特别关注每日脂肪摄入的不平衡情况。

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