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How to interpret a small increase in AUC with an additional risk prediction marker: decision analysis comes through.如何解释 AUC 随着额外风险预测标志物的增加而略有增加:决策分析派上用场。
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本文引用的文献

1
Value of adding single-nucleotide polymorphism genotypes to a breast cancer risk model.将单核苷酸多态性基因型纳入乳腺癌风险模型的价值。
J Natl Cancer Inst. 2009 Jul 1;101(13):959-63. doi: 10.1093/jnci/djp130. Epub 2009 Jun 17.
2
Common 5p15.33 and 6p21.33 variants influence lung cancer risk.常见的5p15.33和6p21.33变异影响肺癌风险。
Nat Genet. 2008 Dec;40(12):1407-9. doi: 10.1038/ng.273. Epub 2008 Nov 2.
3
Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk.用于预测乳腺癌风险的模型中,单核苷酸多态性的鉴别准确性。
J Natl Cancer Inst. 2008 Jul 16;100(14):1037-41. doi: 10.1093/jnci/djn180. Epub 2008 Jul 8.
4
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.标签单核苷酸多态性的全基因组关联扫描在15q25.1处鉴定出一个肺癌易感位点。
Nat Genet. 2008 May;40(5):616-22. doi: 10.1038/ng.109. Epub 2008 Apr 2.
5
Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond.评估新标志物的附加预测能力:从ROC曲线下面积到重新分类及其他。
Stat Med. 2008 Jan 30;27(2):157-72; discussion 207-12. doi: 10.1002/sim.2929.
6
A risk model for prediction of lung cancer.一种用于预测肺癌的风险模型。
J Natl Cancer Inst. 2007 May 2;99(9):715-26. doi: 10.1093/jnci/djk153.
7
Benchmarking lung cancer mortality rates in current and former smokers.对当前吸烟者和既往吸烟者的肺癌死亡率进行基准评估。
Chest. 2004 Dec;126(6):1742-9. doi: 10.1378/chest.126.6.1742.

Re: Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk.

作者信息

Spitz Margaret R, Amos C I, D'Amelio A, Dong Q, Etzel C

出版信息

J Natl Cancer Inst. 2009 Dec 16;101(24):1731-2; author reply 1732. doi: 10.1093/jnci/djp394.

DOI:10.1093/jnci/djp394
PMID:19903803
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2794300/
Abstract
摘要