Lindemann Joerg, Tsakiropoulou Evangelia, Konstantinidis Iordanis, Lindemann Kerstin
Department of Otorhinolaryngology, University of Ulm, Ulm, Germany.
Auris Nasus Larynx. 2010 Jun;37(3):303-7. doi: 10.1016/j.anl.2009.09.012. Epub 2009 Nov 10.
Aging causes changes in nasal morphology and function. This study assesses if the age-related nasal changes are detectable with objective measurements and reflected in two validated quality of life outcome tools: the Nasal Obstruction Symptom Evaluation Scale (NOSE) and the Sino-Nasal Outcome Test (SNOT-20) questionnaires.
Two study groups were included: the "young" group A (n=40) with a mean age of 27 years and the "elder" group B (n=40) with a mean age of 70 years. The subjective nasal complaints and quality of life status were recorded by means of the NOSE and SNOT-20 questionnaires. Objective assessment of intranasal dimensions and nasal airflow in all subjects were performed with the use of acoustic rhinometry and active anterior rhinomanometry respectively.
The values obtained from acoustic rhinometry were significantly higher in the older group compared to the younger, presenting wider nasal airway passages for the elderly. However this was not the case with rhinomanometry values as no significant differences between groups were found. In addition no statistically significant difference was demonstrated in both questionnaires scoring between younger and older subjects.
The outcome of the NOSE and SNOT questionnaires show no deterioration of quality of life in elderly related with changes in nasal function. Acoustic rhinometry confirmed that nasal cavities are becoming larger across the lifespan.
衰老会导致鼻腔形态和功能发生变化。本研究评估与年龄相关的鼻腔变化是否可以通过客观测量检测到,并反映在两种经过验证的生活质量评估工具中:鼻阻塞症状评估量表(NOSE)和鼻-鼻窦结局测试(SNOT-20)问卷。
纳入两个研究组:平均年龄27岁的“年轻”A组(n = 40)和平均年龄70岁的“年长”B组(n = 40)。通过NOSE和SNOT-20问卷记录主观鼻腔症状和生活质量状况。分别使用声反射鼻测量法和主动前鼻测压法对所有受试者的鼻内尺寸和鼻气流进行客观评估。
与年轻组相比,老年组通过声反射鼻测量法获得的值显著更高,表明老年人的鼻气道更宽。然而,鼻测压值并非如此,两组之间未发现显著差异。此外,年轻和老年受试者在两份问卷评分中均未显示出统计学上的显著差异。
NOSE和SNOT问卷的结果表明,老年人的生活质量并未因鼻腔功能变化而下降。声反射鼻测量法证实,鼻腔在整个生命周期中会逐渐变大。