Guralnick Michael L, Grimsby Gwen, Liss Michael, Szabo Aniko, O'Connor R Corey
Department of Urology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Int Urogynecol J. 2010 Mar;21(3):325-9. doi: 10.1007/s00192-009-1030-7. Epub 2009 Nov 12.
This paper aims to determine if there are differences between female overactive bladder (OAB) patients with and without urodynamic detrusor overactivity (DO).
A retrospective chart review was performed on 146 women with OAB. All patients completed an American Urological Association symptom score, 48-h bladder diary (documenting voided volumes, incontinent episodes, and degree of urgency to void), and urodynamic testing (UDS). Patients with urodynamic DO were then compared to patients without DO.
There were no differences in symptom scores. Patients with DO (54.1%) were older (61.8 vs. 50.8 years) and had smaller maximum voided volumes per void (377 mL vs. 476 mL), average 24-h urine output (1,975 mL vs. 2,320 mL), and significantly more incontinent episodes. On UDS, patients with DO were more likely to have abnormal sensation, with strong desire and urgency occurring at significantly lower bladder volumes.
Despite similar symptomatology, there are objective differences between OAB patients with and without DO.
本文旨在确定有尿动力学逼尿肌过度活动（DO）和无尿动力学逼尿肌过度活动的女性膀胱过度活动症（OAB）患者之间是否存在差异。
对146例OAB女性患者进行回顾性病历审查。所有患者均完成了美国泌尿外科学会症状评分、48小时膀胱日记（记录排尿量、尿失禁发作情况及排尿急迫程度）以及尿动力学检查（UDS）。然后将有尿动力学DO的患者与无DO的患者进行比较。
症状评分无差异。有DO的患者（54.1%）年龄更大（61.8岁对50.8岁），每次排尿的最大排尿量更小（377毫升对476毫升），24小时平均尿量更少（1975毫升对2320毫升），且尿失禁发作次数显著更多。在尿动力学检查中，有DO的患者更易出现感觉异常，强烈排尿欲望和急迫感在膀胱容量显著更低时出现。
尽管症状相似，但有DO和无DO的OAB患者之间存在客观差异。
