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糖尿病视网膜病变中的棉絮斑与视网膜光敏感度

Cotton-wool spots and retinal light sensitivity in diabetic retinopathy.

作者信息

Bek T, Lund-Andersen H

机构信息

Department of Ophthalmology, University of Copenhagen, Gentofte Hospital, Hellerup, Denmark.

出版信息

Br J Ophthalmol. 1991 Jan;75(1):13-7. doi: 10.1136/bjo.75.1.13.

DOI:10.1136/bjo.75.1.13
PMID:1991079
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC504098/
Abstract

In 14 eyes of 14 patients with diabetic retinopathy the light sensitivity of retinal cotton-wool spots was studied by computerised perimetry, and the visual field data were accurately correlated with the corresponding morphology as seen on fundus photographs and fluorescein angiograms. In 12 of the eyes the examinations were repeated within one year in order to follow changes in retinal light sensitivity during the evolution of the lesions. Retinal cotton-wool spots were in all eyes associated with localised non-arcuate scotomata in the visual field. In four eyes the cotton-wool spots disappeared within three months of the first examination, and in two of these cases the corresponding scotomata disappeared together with the morphological lesions. In eight eyes the cotton-wool spots (and the corresponding scotomata) had not resolved one year after the first examination. The mean blood pressure showed no significant difference between the patients in whom the lesions resolved within three months and the patients in whom the lesions persisted longer.

摘要

在14例糖尿病性视网膜病变患者的14只眼中,采用计算机视野计研究了视网膜棉絮斑的光敏感度,并将视野数据与眼底照片和荧光素血管造影所见的相应形态进行了精确关联。其中12只眼在1年内重复进行检查,以跟踪病变发展过程中视网膜光敏感度的变化。所有眼中的视网膜棉絮斑均与视野中的局限性非弓形暗点相关。4只眼中的棉絮斑在首次检查后3个月内消失,其中2例相应的暗点随形态学病变一同消失。8只眼中的棉絮斑(及相应的暗点)在首次检查1年后仍未消退。病变在3个月内消退的患者与病变持续时间较长的患者之间,平均血压无显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c9f/504098/08b844ce617a/brjopthal00061-0022-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c9f/504098/b343e5585226/brjopthal00061-0023-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c9f/504098/5072dc620098/brjopthal00061-0021-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c9f/504098/29ec1e34d298/brjopthal00061-0022-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c9f/504098/08b844ce617a/brjopthal00061-0022-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c9f/504098/b343e5585226/brjopthal00061-0023-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c9f/504098/2bb7eb17113e/brjopthal00061-0023-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c9f/504098/97b3d3e07bb3/brjopthal00061-0023-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c9f/504098/196e83c89eb8/brjopthal00061-0020-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c9f/504098/1b0d2f9b50f0/brjopthal00061-0021-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c9f/504098/5072dc620098/brjopthal00061-0021-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c9f/504098/29ec1e34d298/brjopthal00061-0022-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c9f/504098/08b844ce617a/brjopthal00061-0022-b.jpg

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本文引用的文献

1
RETINAL SOFT EXUDATES. A CLINICAL STUDY BY COLOUR AND FLUORESCENCE PHOTOGRAPHY.视网膜软性渗出物。一项通过彩色及荧光摄影的临床研究。
Q J Med. 1964 Jan;33:117-31.
2
TYPES OF EXUDATES IN DIABETIC RETINOPATHY.糖尿病视网膜病变中的渗出物类型
Acta Med Scand. 1963 Sep;174:375-84. doi: 10.1111/j.0954-6820.1963.tb07936.x.
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[Morphology and histochemistry of hard and soft exudates of the retina in diabetes mellitus and essential hypertension].[糖尿病和原发性高血压视网膜硬性及软性渗出物的形态学与组织化学研究]
J Ophthalmic Vis Res. 2014 Apr;9(2):272-5.
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Isolated cotton-wool spots of unknown etiology: management and sequential spectral domain optical coherence tomography documentation.病因不明的孤立性棉絮斑:管理及连续的频域光学相干断层扫描记录
Clin Ophthalmol. 2011;5:1431-3. doi: 10.2147/OPTH.S16272. Epub 2011 Oct 4.
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The mechanisms of vision loss associated with a cotton wool spot.与棉絮斑相关的视力丧失机制。
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Visual field loss after argon laser panretinal photocoagulation in diabetic retinopathy: full- versus mild-scatter coagulation.糖尿病性视网膜病变患者接受氩激光全视网膜光凝术后的视野缺损:全散射与轻度散射光凝的比较
Int Ophthalmol. 1998;22(5):313-9. doi: 10.1023/a:1006367029134.
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Automated static perimetry as a screening method for evaluation of retinal perfusion in diabetic retinopathy.自动静态视野检查作为评估糖尿病视网膜病变视网膜灌注的筛查方法。
Int Ophthalmol. 1997;21(6):305-9. doi: 10.1023/a:1006024305992.
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Cotton-wool spots in diabetic retinopathy.糖尿病性视网膜病变中的棉絮斑。
Diabetes. 1969 Oct;18(10):691-704. doi: 10.2337/diab.18.10.691.
5
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Diabetic cotton-wool spots: an evaluation using perimetric and angiographic techniques.糖尿病性棉絮斑:采用视野计和血管造影技术的评估
Can J Ophthalmol. 1970 Jan;5(1):68-77.
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