Bek T
Department of Ophthalmology, University of Copenhagen, Gentofte Hospital, Denmark.
Acta Ophthalmol (Copenh). 1991 Feb;69(1):11-8. doi: 10.1111/j.1755-3768.1991.tb01984.x.
In 13 patients with diabetic retinopathy who had localised scotomata in the central visual field that could not be ascribed to haemorrhages, cotton wool spots or hard exudates, visual field data obtained by computerised perimetry were correlated with the corresponding retinal morphology as seen on fundus photographs and fluorescein angiograms. It was attempted to relate the retinal areas corresponding to the scotomata to areas of distribution from the central retinal artery. In six cases localised scotomata could be correlated with focal areas of angiographical non-perfusion in the macular area. When these areas of non-perfusion were traversed by a patient vessel, the retinal zone adjacent to this vessel was found to have retained light sensitivity. Two localised scotomata could be correlated with retinal areas peripheral from occluded arterioles, but no scotoma was found which could be related th retinal venous occlusion. In five cases scotomata occurred, however, which could not be related to areas of distribution from the central retinal artery. It is concluded that factors other than retinal vascular occlusion probably are involved in causing impairment of neurosensory function in diabetic maculopathy.
在13例糖尿病性视网膜病变患者中，其中心视野存在局限性暗点，且这些暗点不能归因于出血、棉絮斑或硬性渗出，通过计算机视野计获得的视野数据与眼底照片和荧光素血管造影所见的相应视网膜形态相关。试图将与暗点相对应的视网膜区域与视网膜中央动脉的分布区域联系起来。在6例中，局限性暗点可与黄斑区血管造影无灌注的局灶区域相关。当这些无灌注区域被一条异常血管穿过时，发现与该血管相邻的视网膜区域仍保留光敏感度。2个局限性暗点可与阻塞小动脉周围的视网膜区域相关，但未发现与视网膜静脉阻塞相关的暗点。然而，有5例出现了与视网膜中央动脉分布区域无关的暗点。结论是，除视网膜血管阻塞外，其他因素可能也参与了糖尿病性黄斑病变中神经感觉功能损害的发生。
