Bek T
Department of Ophthalmology, University of Copenhagen, Gentofte Hospital, Hellerup, Denmark.
Acta Ophthalmol (Copenh). 1990 Aug;68(4):421-7. doi: 10.1111/j.1755-3768.1990.tb01670.x.
Fifteen eyes of 15 patients with proliferative diabetic retinopathy within the central 60 degrees of the eye fundus were examined with computerized perimetry, and the visual field data were accurately correlated with the corresponding morphology as seen on fundus photographs and fluorescein angiograms. In 12 out of 13 eyes with neovascularizations outside the optic disc area an absolute scotoma could be correlated with a retinal area distal from the neocascularization, and in one case no scotoma was found in this area. The localized scotomata corresponded in 8 cases to non-perfusion areas as seen on fluorescein angiograms, whereas in 5 cases no pathological morphology was detected in these areas. Seven eyes which had neovascularizations at the optic disc showed the same pattern, but with visual field loss of more pronounced degree. Furthermore, other scotomata which not corresponded to any pathological fundus morphology occurred at approx. 30 degrees eccentricity in the visual field. The findings are discussed in relation to the current hypothesis about the initiation and development of neovascularizations in proliferative diabetic retinopathy.
对15例患有增生性糖尿病视网膜病变且病变位于眼底中央60度范围内的患者的15只眼睛进行了电脑视野检查，并将视野数据与眼底照片和荧光素血管造影所显示的相应形态进行了精确关联。在视盘区域以外有新生血管形成的13只眼睛中，有12只眼睛的绝对暗点与新生血管形成远端的视网膜区域相关，而在1例中该区域未发现暗点。8例局限性暗点与荧光素血管造影上所见的无灌注区域相对应，而在5例中这些区域未检测到病理形态。7只视盘处有新生血管形成的眼睛呈现相同模式，但视野缺损程度更明显。此外，视野中约30度偏心度处出现了其他与任何病理性眼底形态均不对应的暗点。结合当前关于增生性糖尿病视网膜病变新生血管形成起始和发展的假说对这些发现进行了讨论。
