Faculty of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
Clin Oral Implants Res. 2010 Feb;21(2):148-55. doi: 10.1111/j.1600-0501.2009.01812.x. Epub 2009 Nov 13.
The aims of this research were to evaluate the efficacy of a bioactive glass-ceramic (Biosilicate) and a bioactive glass (Biogran) placed in dental sockets in the maintenance of alveolar ridge and in the osseointegration of Ti implants.
Six dogs had their low premolars extracted and the sockets were implanted with Biosilicate, Biogran particles, or left untreated. After the extractions, measurements of width and height on the alveolar ridge were taken. After 12 weeks a new surgery was performed to take the final ridge measurements and to insert bilaterally three Ti implants in biomaterial-implanted and control sites. Eight weeks post-Ti implant placement block biopsies were processed for histological and histomorphometric analysis. The percentages of bone-implant contact (BIC), of mineralized bone area between threads (BABT), and of mineralized bone area within the mirror area (BAMA) were determined.
The presence of Biosilicate or Biogran particles preserved alveolar ridge height without affecting its width. No significant differences in terms of BIC, BAMA, and BABT values were detected among Biosilicate, Biogran, and the non-implanted group.
The results of the present study indicate that filling of sockets with either Biosilicate or Biogran particles preserves alveolar bone ridge height and allows osseointegration of Ti implants.
本研究旨在评估生物活性玻璃陶瓷(Biosilicate)和生物活性玻璃(Biogran)在维持牙槽嵴和钛种植体骨整合方面的疗效。
6 只狗的低前磨牙被拔出,牙槽窝中植入 Biosilicate、Biogran 颗粒或不做处理。拔牙后,测量牙槽嵴的宽度和高度。12 周后,进行新的手术以获得最终的牙槽嵴测量值,并在生物材料植入和对照部位双侧植入三个 Ti 种植体。植入 Ti 种植体 8 周后,进行块状组织学和组织形态计量学分析。确定骨-种植体接触率(BIC)、螺纹间矿化骨面积(BABT)和镜像区矿化骨面积(BAMA)的百分比。
Biosilicate 或 Biogran 颗粒的存在保持了牙槽嵴的高度,而不影响其宽度。Biosilicate、Biogran 和未植入组之间在 BIC、BAMA 和 BABT 值方面没有显著差异。
本研究结果表明,用 Biosilicate 或 Biogran 颗粒填充牙槽窝可以保持牙槽骨嵴的高度,并允许 Ti 种植体的骨整合。