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一项关于智力残疾成年人睡眠问题患病率的队列研究。

A cohort study of the prevalence of sleep problems in adults with intellectual disabilities.

机构信息

Section of Psychological Medicine, Faculty of Medicine, University of Glasgow, Glasgow, UK.

出版信息

J Sleep Res. 2010 Mar;19(1 Pt 1):42-53. doi: 10.1111/j.1365-2869.2009.00788.x. Epub 2009 Nov 11.

Abstract

Previous studies of the prevalence of sleep problems in adults with intellectual disabilities (ID) are affected by small, potentially biased samples and other limitations. This study aims to determine the prevalence and associations of sleep problems in the adult population with ID. The 4-week period prevalence of sleep problems was determined in a cross-sectional study of all adults with ID in a defined geographical area. Sleep problems were identified using the Psychiatric Assessment Scale for Adults with Developmental Disabilities (PAS-ADD) checklist and categorized as initial insomnia, early morning wakening and broken sleep. A fourth, composite, variable of significant sleep problem was also derived. Of the 1023 adults with ID who participated, 9.2% had experienced a significant sleep problem, during the 1-month period. Individuals with a significant sleep problem are more likely to have mental ill-health [odds ratio (OR) = 5.53, 95% confidence interval (CI) 3.52-8.69], problem behaviours (OR = 2.06, 95% CI: 1.25-3.41) and respiratory disease (OR = 2.03, 95% CI: 1.27-3.26). There is a positive association between visual impairment and initial insomnia (OR = 1.91, 95% CI: 1.21-3.04). Although a diagnosis of epilepsy is not associated with sleep problems, the finding that individuals taking antiepileptic medication are more likely to experience broken sleep (OR = 1.73, 95% CI: 1.13-2.66) suggests that medication side effects may impact on sleep of individuals with ID. The results suggest that there is a need to further examine the relationship between sleep problems and co-morbid health problems, which would inform the development of interventions, and trials of their efficacy.

摘要

先前关于智力障碍(ID)成人睡眠问题患病率的研究受到小样本和其他局限性的影响。本研究旨在确定特定地理区域内 ID 成人人群中睡眠问题的患病率及其相关性。使用成人发育障碍精神病学评估量表(PAS-ADD)清单确定横断面研究中所有 ID 成人的 4 周内睡眠问题的患病率,并将其分类为初始失眠、清晨早醒和睡眠中断。还衍生出一个第四种、综合的、显著睡眠问题变量。在参与的 1023 名 ID 成人中,有 9.2%的人在 1 个月期间经历了显著的睡眠问题。有显著睡眠问题的个体更有可能存在心理健康问题[比值比(OR)=5.53,95%置信区间(CI)3.52-8.69]、行为问题(OR=2.06,95%CI:1.25-3.41)和呼吸系统疾病(OR=2.03,95%CI:1.27-3.26)。视力障碍与初始失眠呈正相关(OR=1.91,95%CI:1.21-3.04)。尽管癫痫诊断与睡眠问题无关,但发现服用抗癫痫药物的个体更有可能出现睡眠中断(OR=1.73,95%CI:1.13-2.66),这表明药物副作用可能会影响 ID 个体的睡眠。研究结果表明,有必要进一步研究睡眠问题与合并健康问题之间的关系,这将有助于制定干预措施,并对其疗效进行试验。

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