Plante Ianik, Cucinotta Francis A
NASA Johnson Space Center, 2101 NASA Parkway, Houston, TX 77058, USA,
Radiat Environ Biophys. 2010 Mar;49(1):5-13. doi: 10.1007/s00411-009-0255-7.
Radiation track structure simulations have been used for many years to study the DNA damage caused by heavy ions. These studies are highly relevant for treatment planning of heavy ion radiotherapy and space radiation risk assessment. Measurements of the frequency of delta-rays hits, mean specific energy per target hits and per ion, and the frequency of dose distribution in a cylindrical target volume placed at various radial distances from 4He 2+, 12C 6+ and 16O 8+ tracks have been performed by Schmollack et al. (in Radiat Res 153:469-478, 2000). In the present work, Monte Carlo simulation of radiation tracks has been performed with the RITRACKS and the RETRACKS codes along with a target volume to simulate the experiment of Schmollack et al. The results of these simulations are compared to those of previous deterministic models of the radial dependence of the mean specific energy. Our Monte Carlo simulations are consistent with the experimental data both in the core and in the penumbra of the beam, and are shown to provide a better description of the experimental data than deterministic codes.
辐射径迹结构模拟多年来一直被用于研究重离子引起的DNA损伤。这些研究对于重离子放射治疗的治疗计划和空间辐射风险评估具有高度相关性。Schmollack等人（《放射研究》153:469 - 478，2000年）对位于距4He 2+、12C 6+和16O 8+径迹不同径向距离处的圆柱形靶体积内的δ射线击中频率、每个靶击中及每个离子的平均比能以及剂量分布频率进行了测量。在本工作中，使用RITRACKS和RETRACKS代码以及一个靶体积进行了辐射径迹的蒙特卡罗模拟，以模拟Schmollack等人的实验。将这些模拟结果与先前关于平均比能径向依赖性的确定性模型结果进行了比较。我们的蒙特卡罗模拟在束流的核心和半影区均与实验数据一致，并且显示出比确定性代码能更好地描述实验数据。
