Visual Function Laboratory, Glaucoma Research Center, Department of Ophthalmology, University of California, San Diego, California, U. S. A.
J Glaucoma. 1994 Summer;3 Suppl 1:S5-18.
Several investigators have described significant changes in visual function in ocular hypertensive and glaucoma-suspect eyes even though standard visual fields remain normal. Functional deficits in color vision, color visual fields, contrast sensitivity, flicker sensitivity, resolution, and motion detection have been documented. We review here the results from our laboratory and other laboratories on several of these tests. The relationship of these deficits to underlying physiology and a current theory that magnocellular fibers are damaged early in glaucoma are discussed. The evidence suggests that by the time glaucoma is diagnosed, based on characteristic changes in the optic disc, standard visual fields, and increased intraocular pressure, several visual functions are compromised. It is time to review the implications of these findings for diagnosis and management of glaucoma.
一些研究人员已经描述了即使标准视野仍然正常,在高眼压和疑似青光眼眼中视觉功能的显著变化。已经记录了在色觉、色视野、对比敏感度、闪烁敏感度、分辨率和运动检测方面的功能缺陷。我们在这里回顾了我们实验室和其他实验室在这些测试中的一些结果。讨论了这些缺陷与潜在生理学的关系,以及大细胞纤维在青光眼早期受损的现有理论。有证据表明,当青光眼根据视盘、标准视野和眼压升高的特征性变化来诊断时,已经有几种视觉功能受到了损害。现在是时候重新审视这些发现对青光眼诊断和治疗的影响了。