Service of Therapeutic Education for Chronic Diseases, WHO Collaborating Centre, Department of Community Medicine and Primary Care, University Hospitals of Geneva, Geneva, Switzerland.
Dig Surg. 2009;26(5):430-3. doi: 10.1159/000237746. Epub 2009 Nov 13.
BACKGROUND/AIMS: Improving health-related quality of life (HRQoL) along with decreasing obesity-related morbidity is one of the cornerstones of bariatric surgery. The aim of the study was to investigate how losing weight influences the HRQoL 1 year after gastric bypass and whether HRQoL prior to surgery predicts the amount of weight loss 1 year after gastric bypass.
One hundred and thirty-nine obese women [median (range): age 45 years (20-71), BMI 44 (29-88)] admitted for gastric bypass were selected prospectively and completed the Nottingham Health Profile (NHP) quality of life questionnaire before and 1 year after surgery.
Weight loss 1 year after gastric bypass was significant [-37 kg (9-74), p < 0.001] and led to an improvement of quality of life [NHP total score before surgery 62 (39-76) and after surgery 20 (7-65), p < 0.001].
HRQoL improves dramatically 1 year after gastric bypass. This HRQoL improvement is not influenced by the amount of weight loss, but rather by the BMI achieved at that time.
背景/目的：提高与肥胖相关的发病率的同时改善健康相关生活质量（HRQoL）是减重手术的基石之一。本研究的目的是探讨胃旁路术后 1 年体重减轻如何影响 HRQoL，以及手术前的 HRQoL 是否预测胃旁路术后 1 年的体重减轻量。
前瞻性选择 139 名接受胃旁路手术的肥胖女性[中位数（范围）：年龄 45 岁（20-71），BMI 44（29-88）]，并在手术前和手术后 1 年完成诺丁汉健康调查问卷（NHP）生活质量问卷。
胃旁路术后 1 年的体重减轻量显著[-37kg（9-74），p<0.001]，并导致生活质量的改善[NHP 术前总评分 62（39-76）和术后 20（7-65），p<0.001]。
胃旁路术后 1 年 HRQoL 显著改善。这种 HRQoL 的改善不受体重减轻量的影响，而是由当时达到的 BMI 决定。
