Department of Family Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.
J Chin Med Assoc. 2011 Apr;74(4):169-75. doi: 10.1016/j.jcma.2011.01.038. Epub 2011 Mar 17.
Obesity is a worldwide public health issue, and the prevalence of obesity is also increasing steadily in Taiwan. Obesity leads to several chronic diseases. Often, impaired quality of life is a consequence of obesity. The aim of this study was to determine if body weight-loss could improve health-related quality of life (HRQOL) in Taiwan.
The cutoff for obesity is body mass index (BMI) = 27 as compared with 30 in US and Europe. We enrolled 67 participants with BMI ≥ 27 and more than one criterion of the metabolic syndrome, who underwent 3 months of body weight-loss intervention by diet control and regular exercise. We performed anthropometric measurements and blood tests, and administered the WHOQOL-BREF questionnaire Taiwanese version to assess HRQOL before and after the weight loss intervention. This is the first study using the WHOQOL-BREF to examine HRQOL in Taiwan. The questionnaire included D1 physical, D2 psychological, D3 social relationships and D4 environmental domains; each was scored from 4 to 20.
Obese subjects had lower D1 and D2 scores as compared with the Taiwan healthy population reference group at baseline. In this study, 38 participants completed the 3-month intervention program and 29 participants dropped out. Twenty-five participants reached the 5% of initial BMI goal. Among them, significant statistical improvements were found both in medical comorbidities and in the four domains of the HRQOL questionnaire.
Obesity can cause impaired HRQOL, which can be improved through BMI intervention. In addition to the benefits of biomedical aspect, this could be an incentive goal for keeping body weight control.
肥胖是一个全球性的公共卫生问题,台湾的肥胖患病率也在稳步上升。肥胖会导致多种慢性疾病,往往会导致生活质量受损。本研究旨在探讨体重减轻是否能改善台湾的健康相关生活质量(HRQOL)。
肥胖的标准是体重指数(BMI)≥27,而美国和欧洲的标准是 BMI≥30。我们招募了 67 名 BMI≥27 且符合代谢综合征标准之一的参与者,他们接受了 3 个月的饮食控制和定期运动的体重减轻干预。我们进行了人体测量和血液测试,并使用世界卫生组织生活质量简表(WHOQOL-BREF)台湾版评估体重减轻干预前后的 HRQOL。这是首次使用 WHOQOL-BREF 量表来评估台湾的 HRQOL。问卷包括 D1 生理、D2 心理、D3 社会关系和 D4 环境领域;每个领域的得分从 4 到 20。
肥胖受试者在基线时的 D1 和 D2 评分低于台湾健康人群参考组。在这项研究中,38 名参与者完成了 3 个月的干预计划,29 名参与者中途退出。25 名参与者达到了初始 BMI 目标的 5%。其中,在医学合并症和 HRQOL 问卷的四个领域都发现了显著的统计学改善。
肥胖会导致 HRQOL 受损,通过 BMI 干预可以改善。除了生物医学方面的好处外,这也可以成为控制体重的激励目标。