Centers for Disease Control and Prevention, Office of Workforce and Career Development, Career Development Division, Epidemic Intelligence Service, 1600 Clifton Rd. NE, Atlanta, GA 30333, USA.
Vaccine. 2009 Nov 27;27(51):7156-61. doi: 10.1016/j.vaccine.2009.09.028.
The United States of America (USA) does not have a national reporting system for rabies post-exposure prophylaxis (PEP). We describe the epidemiology of PEP in the USA so recommendations can be made during a PEP shortage.
A two-part questionnaire designed to evaluate PEP distribution practices and estimate PEP use was administered to state health department representatives.
Seventy-five percent of participants responded that no public health guidance was needed to make a recommendation for PEP. The annual national average PEP use is 23,415 courses of PEP (range: 10,645-35,845).
PEP is loosely monitored and a precise estimate of PEP use is unknown. Improved national surveillance for PEP is needed.
美国没有全国性的狂犬病暴露后预防 (PEP) 报告系统。我们描述了美国 PEP 的流行病学情况，以便在 PEP 短缺期间提出建议。
设计了一个两部分的问卷，旨在评估 PEP 分布实践并估计 PEP 的使用情况，分发给州卫生部门代表。
75%的参与者表示，无需公共卫生指导即可推荐使用 PEP。全国每年 PEP 的平均使用量为 23415 个疗程（范围：10645-35845）。
PEP 的监测较为宽松，对 PEP 使用的准确估计尚不清楚。需要改进全国范围内的 PEP 监测。
