狂犬病暴露后预防的流行病学——美国，2006-2008 年。
Epidemiology of rabies post-exposure prophylaxis--United States of America, 2006-2008.
机构信息
Centers for Disease Control and Prevention, Office of Workforce and Career Development, Career Development Division, Epidemic Intelligence Service, 1600 Clifton Rd. NE, Atlanta, GA 30333, USA.
出版信息
Vaccine. 2009 Nov 27;27(51):7156-61. doi: 10.1016/j.vaccine.2009.09.028.
BACKGROUND
The United States of America (USA) does not have a national reporting system for rabies post-exposure prophylaxis (PEP). We describe the epidemiology of PEP in the USA so recommendations can be made during a PEP shortage.
METHODS
A two-part questionnaire designed to evaluate PEP distribution practices and estimate PEP use was administered to state health department representatives.
RESULTS
Seventy-five percent of participants responded that no public health guidance was needed to make a recommendation for PEP. The annual national average PEP use is 23,415 courses of PEP (range: 10,645-35,845).
CONCLUSION
PEP is loosely monitored and a precise estimate of PEP use is unknown. Improved national surveillance for PEP is needed.
背景
美国没有全国性的狂犬病暴露后预防 (PEP) 报告系统。我们描述了美国 PEP 的流行病学情况，以便在 PEP 短缺期间提出建议。
方法
设计了一个两部分的问卷，旨在评估 PEP 分布实践并估计 PEP 的使用情况，分发给州卫生部门代表。
结果
75%的参与者表示，无需公共卫生指导即可推荐使用 PEP。全国每年 PEP 的平均使用量为 23415 个疗程（范围：10645-35845）。
结论
PEP 的监测较为宽松，对 PEP 使用的准确估计尚不清楚。需要改进全国范围内的 PEP 监测。
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