可调谐光谱的无泄漏金纳米容器。
Spectrally tunable leakage-free gold nanocontainers.
机构信息
Department of Bioengineering, University of Washington, William H. Foege Building N530M, Seattle, Washington 98195, USA.
出版信息
J Am Chem Soc. 2009 Dec 16;131(49):17774-6. doi: 10.1021/ja9076765.
Abstract
Drug delivery with precise spatial and temporal control is of broad current interest in biology and medicine. Despite recent advances achieved by combining drugs or drug carriers with NIR light responsive plasmonic nanomaterials, existing technologies are not capable of preventing drug leakage or degradation. We report a new class of monodisperse gold nanocontainer that can stably encapsulate cargo molecules, yet is compact in size and tunable in spectral responses.
摘要
药物输送的精确时空控制在生物学和医学领域具有广泛的当前兴趣。尽管通过将药物或药物载体与近红外光响应的等离子体纳米材料结合已经取得了最近的进展，但现有的技术还不能防止药物泄漏或降解。我们报告了一类新的单分散金纳米容器，它可以稳定地封装货物分子，同时尺寸紧凑，光谱响应可调。
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