英国全国急性扁桃体炎和扁桃体周围脓肿抗生素处方调查。
National UK survey of antibiotics prescribed for acute tonsillitis and peritonsillar abscess.
作者信息
Visvanathan V, Nix P
机构信息
Department of ENT/Head and Neck Surgery, Leeds Teaching Hospitals NHS Trust, Leeds General Infirmary, Leeds, West Yorkshire, LS1 3EX. UK.
出版信息
J Laryngol Otol. 2010 Apr;124(4):420-3. doi: 10.1017/S0022215109991939. Epub 2009 Nov 25.
AIM
To survey antibiotics prescribed for patients admitted with acute tonsillitis and peritonsillar abscess to UK ENT departments.
MATERIALS AND METHODS
An anonymous postal questionnaire was sent to UK ENT consultants.
RESULTS
Intravenous benzylpenicillin alone was preferred significantly more often for acute tonsillitis (n = 175) than for peritonsillar abscess (83) (p < 0.001). A combination of benzylpenicillin and metronidazole was preferred significantly more often for peritonsillar abscess (n = 131) than for tonsillitis (62) (p < 0.001).
CONCLUSIONS
In this survey, penicillin was the commonest antibiotic choice for tonsillitis; this is in accordance with published guidelines. For cases of peritonsillar abscess, benzylpenicillin with metronidazole was the most common antibiotic combination chosen. However, the high resolution rate of peritonsillar abscess following drainage and treatment with penicillin alone suggests that multiple antibiotics are unnecessary and inappropriate in this setting.
目的
调查英国耳鼻喉科收治的急性扁桃体炎和扁桃体周脓肿患者所使用的抗生素。
材料与方法
向英国耳鼻喉科顾问发送匿名邮寄问卷。
结果
单纯静脉注射苄星青霉素用于急性扁桃体炎（n = 175）的频率显著高于扁桃体周脓肿（83）（p < 0.001）。苄星青霉素与甲硝唑联合使用用于扁桃体周脓肿（n = 131）的频率显著高于扁桃体炎（62）（p < 0.001）。
结论
在本次调查中，青霉素是扁桃体炎最常用的抗生素选择；这与已发表的指南一致。对于扁桃体周脓肿病例，苄星青霉素与甲硝唑是最常用的抗生素组合。然而，单纯青霉素引流及治疗后扁桃体周脓肿的高治愈率表明，在这种情况下使用多种抗生素是不必要且不合适的。
Zotero 插件