Karacabey Kursat
Higher School of Physical Education and Sports, Gaziantep University, Gaziantep, Turkey.
J Int Med Res. 2009 Sep-Oct;37(5):1472-8. doi: 10.1177/147323000903700523.
This prospective, randomized study investigated the effect of exercise on leptin, insulin, cortisol and lipid profiles in obese children. A total of 40 obese boys aged 10 - 12 years with a body mass index (BMI) >or= 30 kg/m(2) were randomly separated into an exercise group (n = 20) that underwent a 12-week aerobic exercise programme and a non-exercise (control) group (n = 20). The BMI, low-density lipoprotein, cortisol, leptin and insulin levels were significantly lower in the exercise group after 12 weeks compared with baseline values, whereas high-density lipoprotein levels were significantly higher. In contrast, in the control group, low-density lipoprotein, cortisol and leptin levels were significantly higher after 12 weeks compared with baseline values while high-density lipoprotein levels were significantly lower. These findings indicate the importance of regular exercise in the regulation of body weight and protection against cardiovascular risk factors in obese children.
这项前瞻性随机研究调查了运动对肥胖儿童瘦素、胰岛素、皮质醇和血脂水平的影响。共有40名10至12岁、体重指数（BMI）≥30kg/m²的肥胖男孩被随机分为运动组（n = 20）和非运动（对照）组（n = 20），运动组进行了为期12周的有氧运动计划。12周后，运动组的BMI、低密度脂蛋白、皮质醇、瘦素和胰岛素水平与基线值相比显著降低，而高密度脂蛋白水平显著升高。相比之下，对照组在12周后低密度脂蛋白、皮质醇和瘦素水平与基线值相比显著升高，而高密度脂蛋白水平显著降低。这些发现表明定期运动对于肥胖儿童体重调节和预防心血管危险因素具有重要意义。
