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相位移动治疗耳蜗源性耳鸣。

Phase-shift treatment for tinnitus of cochlear origin.

机构信息

University Department of Otorhinolaryngology and Head and Neck Surgery, Brain Research Center Antwerp for Innovative and Interdisciplinary Neuromodulation (BRAI(2)N), Antwerp University Hospital (UZA), University of Antwerp, Wilrijkstraat 10, 2650, Edegem, Antwerp, Belgium.

出版信息

Eur Arch Otorhinolaryngol. 2010 Jun;267(6):881-8. doi: 10.1007/s00405-009-1145-y. Epub 2009 Nov 24.

Abstract

Phase-shift treatment is a new tinnitus therapy that aims at sound cancelling. This technique is based on a theory advocating that the induction of a sound wave with a 180 degrees phase-shift compared to the sound experienced by the patient could result in sound cancelling, likely by negation of the cortical perception of tinnitus or residual inhibition, which can be partial or complete. The aim of our study is to compare the effect of phase-shifting generated by the tinnitus phase-out device between pure tone tinnitus patients (PTP) and narrow band noise tinnitus patients (NBNP). In present comparative study, we explore the effects of phase-shifting during 6 weeks of phase-out therapy in PTP and NBNP. Thirty-five tinnitus patients were included in the study. Twenty-one patients had pure tone tinnitus and 14 patients had narrow band noise tinnitus. The effects on tinnitus were assessed using three separate visual analogue scales (VAS), the tinnitus questionnaire, the hyperacusis questionnaire, the Beck depression inventory, a categorical scale and audiometric measurements. While no differences in VAS were seen after therapy in NBNP, tinnitus increase could be demonstrated in PTP. This increase could be demonstrated for tinnitus loudness (p = 0.002) and tinnitus annoyance (p = 0.014). In conclusion, implementation of phase-shifting did not lead to significant sound cancelling. Our results are discussed and compared to previous studies investigating the effects of phase-out in tinnitus patients.

摘要

移相治疗是一种新的耳鸣治疗方法,旨在实现声音抵消。该技术基于一种理论,即与患者所经历的声音相比,诱导相位相差 180 度的声波可能会导致声音抵消,可能通过否定耳鸣或残留抑制的皮质感知来实现,这种抑制可以是部分的或完全的。我们的研究目的是比较耳鸣消退仪产生的移相在纯音耳鸣患者(PTP)和窄带噪声耳鸣患者(NBNP)中的效果。在目前的比较研究中,我们探索了在 PTP 和 NBNP 中进行 6 周的消退治疗期间移相的效果。研究纳入了 35 名耳鸣患者。21 名患者患有纯音耳鸣,14 名患者患有窄带噪声耳鸣。使用三个单独的视觉模拟量表(VAS)、耳鸣问卷、听敏度问卷、贝克抑郁量表、分类量表和听力测量来评估耳鸣的影响。虽然在 NBNP 患者中,治疗后 VAS 没有差异,但可以证明 PTP 患者的耳鸣增加。可以证明耳鸣响度(p = 0.002)和耳鸣烦恼(p = 0.014)增加。总之,移相的实施并没有导致明显的声音抵消。我们的结果进行了讨论,并与之前研究中调查耳鸣患者消退效果的研究进行了比较。

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