1978年至1988年的10个流行年份中，由B2亚组呼吸道合胞病毒引起的单季流行。
A single-season epidemic with respiratory syncytial virus subgroup B2 during 10 epidemic years, 1978 to 1988.
作者信息
Mufson M A, Akerlind-Stopner B, Orvell C, Belshe R B, Norrby E
机构信息
Marshall University School of Medicine, Huntington, West Virginia 25071.
出版信息
J Clin Microbiol. 1991 Jan;29(1):162-5. doi: 10.1128/jcm.29.1.162-165.1991.
Abstract
Respiratory syncytial virus strains isolated from infants and children hospitalized with acute respiratory tract disease in Huntington, W. Va., from July 1979 through June 1988 were categorized by subgroup by using two panels of monoclonal antibodies specific for subgroup A and subgroup B. Of 405 strains tested, 319 (78.8%) were subgroup A, 73 (18.0%) were subgroup B1, and 13 (3.2%) were subgroup B2. The subgroup B2 strains occurred as a single-season epidemic during the epidemiologic year July 1980 to June 1981, except for one strain isolated in the epidemiologic year 1978 to 1979. Subgroup B strains were associated with significantly fewer bronchiolitis illnesses than subgroup A strains. The severity of illnesses caused by subgroup B1 and B2 strains was the same.
摘要
1979年7月至1988年6月期间，从西弗吉尼亚州亨廷顿因急性呼吸道疾病住院的婴幼儿中分离出的呼吸道合胞病毒毒株，通过使用两组分别针对A亚组和B亚组的单克隆抗体，按亚组进行了分类。在检测的405株毒株中，319株（78.8%）为A亚组，73株（18.0%）为B1亚组，13株（3.2%）为B2亚组。B2亚组毒株在1980年7月至1981年6月的流行病学年度中呈单季流行，1978年至1979年流行病学年度分离出的一株除外。B亚组毒株所致细支气管炎疾病明显少于A亚组毒株。B1亚组和B2亚组毒株所致疾病的严重程度相同。
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